Correlation between Mitochondrial Dysfunction, Cardiovascular Diseases, and Traditional Chinese Medicine
Joint Authors
Chen, Zhigang
Han, Keli
Zhu, Li
Sun, Siyu
Wang, Xiulong
Li, Dongxu
Lin, Fei
Zhao, Guo-An
Li, Xuefang
Li, Yan
Zhao, Yilin
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-08
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Cardiovascular disease (CVD) is the number one threat that seriously endangers human health.
However, the mechanism of their occurrence is not completely clear.
Increasing studies showed that mitochondrial dysfunction is closely related to CVD.
Possible causes of mitochondrial dysfunction include oxidative stress, Ca2+ disorder, mitochondrial DNA mutations, and reduction of mitochondrial biosynthesis, all of which are closely related to the development of CVD.
At present, traditional Chinese medicine (TCM) is widely used in the treatment of CVD.
TCM has the therapeutic characteristics of multitargets and multipathways.
Studies have shown that TCM can treat CVD by protecting mitochondrial function.
Via systematic literature review, the results show that the specific mechanisms include antioxidant stress, regulation of calcium homeostasis, antiapoptosis, and regulation of mitochondrial biosynthesis.
This article describes the relationship between mitochondrial dysfunction and CVD, summarizes the TCM commonly used for the treatment of CVD in recent years, and focuses on the regulatory effect of TCM on mitochondrial function.
American Psychological Association (APA)
Zhu, Li& Chen, Zhigang& Han, Keli& Zhao, Yilin& Li, Yan& Li, Dongxu…[et al.]. 2020. Correlation between Mitochondrial Dysfunction, Cardiovascular Diseases, and Traditional Chinese Medicine. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1155465
Modern Language Association (MLA)
Zhu, Li…[et al.]. Correlation between Mitochondrial Dysfunction, Cardiovascular Diseases, and Traditional Chinese Medicine. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1155465
American Medical Association (AMA)
Zhu, Li& Chen, Zhigang& Han, Keli& Zhao, Yilin& Li, Yan& Li, Dongxu…[et al.]. Correlation between Mitochondrial Dysfunction, Cardiovascular Diseases, and Traditional Chinese Medicine. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1155465
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155465