Serum Creatinine Level and APACHE-II Score within 24 h of Admission Are Effective for Predicting Persistent Organ Failure in Acute Pancreatitis
Joint Authors
Zhu, Yin
Wan, Jian-Hua
Lu, Nong-Hua
Shu, Wenqing
He, Wenhua
Zhu, Yong
Zeng, Hao
Liu, Pi
Xia, Liang
Source
Gastroenterology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Aim.
The present study was aimed at comparing serum markers and APACHE-II score to predict persistent organ failure (POF) in early acute pancreatitis (AP).
Methods.
In this retrospective study, data from 6024 patients with AP were included within 24 h of their admission.
Serum levels of urea nitrogen (BUN), creatinine, glucose, and hematocrit and APACHE-II score were analyzed for patients with AP.
We employed the area under the receiver operating characteristic (ROC) curve (AUC), sensitivity, and specificity analyses to evaluate the accuracy of the studied laboratory parameters and APACHE-II score.
Results.
Our study included 2090 (35%) patients out of 6024 patients who were evaluated within 24 h of hospital admission.
For predicting POF, serum creatinine level≥1.8 mg/dl had the highest specificity (98%).
The second classification tree has shown that when the serum creatinine level>1.8 and APACHE−II≥8 within 24 h were combined, the rates of predicted persistent organ failure achieved 66.7%.
Conclusions.
In this large, hospital-based retrospective study, we demonstrated that an APACHE-II score≥8 and a serum creatinine level≥1.8 mg/dl within 24 h of admission can positively predict POF in AP and that serum creatinine levels<1.8 mg/dl within 24 h of admission can be useful for negatively predicting POF in AP.
American Psychological Association (APA)
Wan, Jian-Hua& Shu, Wenqing& He, Wenhua& Zhu, Yin& Zhu, Yong& Zeng, Hao…[et al.]. 2019. Serum Creatinine Level and APACHE-II Score within 24 h of Admission Are Effective for Predicting Persistent Organ Failure in Acute Pancreatitis. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1155474
Modern Language Association (MLA)
Wan, Jian-Hua…[et al.]. Serum Creatinine Level and APACHE-II Score within 24 h of Admission Are Effective for Predicting Persistent Organ Failure in Acute Pancreatitis. Gastroenterology Research and Practice No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1155474
American Medical Association (AMA)
Wan, Jian-Hua& Shu, Wenqing& He, Wenhua& Zhu, Yin& Zhu, Yong& Zeng, Hao…[et al.]. Serum Creatinine Level and APACHE-II Score within 24 h of Admission Are Effective for Predicting Persistent Organ Failure in Acute Pancreatitis. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1155474
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155474