Resectability of Rectal Neuroendocrine Tumors Using Endoscopic Mucosal Resection with a Ligation Band Device and Endoscopic Submucosal Dissection
Joint Authors
Song, Geun Am
Kim, Gwang Ha
Park, Do Youn
Lee, Bong Eun
Lim, Hong Kyu
Lee, Seong Jun
Baek, Dong Hoon
Park, Eun Young
Park, Joon Woo
Source
Gastroenterology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-16
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Rectal neuroendocrine tumors NETs<10 mm in diameter, limited to the submucosa without local or distant metastasis, can be treated endoscopically.
Endoscopic mucosal resection with a ligation band device (EMR-L) and endoscopic submucosal dissection (ESD) have been employed to resect rectal NETs.
We evaluated and compared the clinical outcomes of EMR-L and ESD for endoscopic resection of rectal NETs G1<10 mm in diameter.
Methods.
We conducted a retrospective study of 82 rectal NETs in 82 patients who underwent either EMR-L or ESD.
Therapeutic outcomes (en bloc resection and complete resection rates), procedure time, and procedure-related adverse events were evaluated.
Additionally, we measured the distance of the lateral and vertical margins from the border of the tumor in pathologic specimens and compared the resectability between EMR-L and ESD.
Results.
Sixty-six lesions were treated using EMR-L and 16 using ESD.
En bloc resection was achieved in all patients.
The complete resection rate with EMR-L was significantly higher than that with ESD (95.5% vs.75.0%, p=0.025).
The prevalence of vertical margin involvement was significantly higher in the ESD group than in the EMR-L group (12.5% vs.
0%, p=0.036), and ESD was more time consuming than EMR-L (24.21±12.18 vs.
7.05±4.53 min, p<0.001).
The lateral and vertical margins were more distant in the EMR-L group than in the ESD group (lateral margin distance, 1661±849 vs.
1514±948 μm; vertical margin distance, 277±308 vs.
202±171 μm).
Conclusions.
EMR-L is more favorable for small rectal NETs with respect to therapeutic outcomes, procedure time, and technical difficulties.
Additionally, EMR-L enables achievement of sufficient vertical margin distances.
American Psychological Association (APA)
Lim, Hong Kyu& Lee, Seong Jun& Baek, Dong Hoon& Park, Do Youn& Lee, Bong Eun& Park, Eun Young…[et al.]. 2019. Resectability of Rectal Neuroendocrine Tumors Using Endoscopic Mucosal Resection with a Ligation Band Device and Endoscopic Submucosal Dissection. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1155510
Modern Language Association (MLA)
Lim, Hong Kyu…[et al.]. Resectability of Rectal Neuroendocrine Tumors Using Endoscopic Mucosal Resection with a Ligation Band Device and Endoscopic Submucosal Dissection. Gastroenterology Research and Practice No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1155510
American Medical Association (AMA)
Lim, Hong Kyu& Lee, Seong Jun& Baek, Dong Hoon& Park, Do Youn& Lee, Bong Eun& Park, Eun Young…[et al.]. Resectability of Rectal Neuroendocrine Tumors Using Endoscopic Mucosal Resection with a Ligation Band Device and Endoscopic Submucosal Dissection. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1155510
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155510