Analgesic and Anti-Inflammatory Activities of Diethyl Ether and n-Hexane Extract of Polyalthia suberosa Leaves
Joint Authors
Aziz, Md. Abdullah
Yasmen, Nelufar
Tajmim, Afsana
Akter, Mst. Irin
Hazra, Amit Kumar
Rahman, S. M. Mushiur
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
In folk medicine, Polyalthia suberosa is used as abortifacient, laxative, febrifuge analgesic, filler of tooth cavities, and anti-HIV drug and for rheumatism and various skin infections.
The present study was directed to evaluate the analgesic and anti-inflammatory activities of diethyl ether and n-hexane extracts of Polyalthia suberosa leaves (PSDE and PSNH).
A variety of tests including formalin-induced paw licking test, acetic acid induced writhing test, and tail immersion test were used to assess the analgesic activity.
In addition, xylene-induced ear edema test was used to evaluate anti-inflammatory activity of PSDE and PSNH.
PSDE and PSNH at 200 and 400 mg/kg doses expressed analgesic as well as anti-inflammatory activities in mice.
In formalin-induced paw licking test, acetic acid induced writhing test, and xylene-induced ear edema test, the extracts exhibited significant inhibition (P⁎<0.05 versus control) of pain and inflammation.
Alternatively, in tail immersion test, PSDE 400 mg/kg showed significant (P⁎<0.05 versus control) latency at 30 min but another tested sample had no significant latency.
From this study, it could be shown that Polyalthia suberosa leaves may contain analgesic and anti-inflammatory agents which support its use in traditional medicine.
American Psychological Association (APA)
Yasmen, Nelufar& Aziz, Md. Abdullah& Tajmim, Afsana& Akter, Mst. Irin& Hazra, Amit Kumar& Rahman, S. M. Mushiur. 2018. Analgesic and Anti-Inflammatory Activities of Diethyl Ether and n-Hexane Extract of Polyalthia suberosa Leaves. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1155561
Modern Language Association (MLA)
Yasmen, Nelufar…[et al.]. Analgesic and Anti-Inflammatory Activities of Diethyl Ether and n-Hexane Extract of Polyalthia suberosa Leaves. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1155561
American Medical Association (AMA)
Yasmen, Nelufar& Aziz, Md. Abdullah& Tajmim, Afsana& Akter, Mst. Irin& Hazra, Amit Kumar& Rahman, S. M. Mushiur. Analgesic and Anti-Inflammatory Activities of Diethyl Ether and n-Hexane Extract of Polyalthia suberosa Leaves. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1155561
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155561