Effect of Acupuncture at LR3 on Cerebral Glucose Metabolism in a Rat Model of Hypertension: A 18F-FDG-PET Study
Joint Authors
Lai, Xin-Sheng
Peng, Chong
Li, Jing
Wang, Yumei
He, Kejie
Wu, Peilong
Li, Chenyun
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Our objective was to investigate the effect of acupuncture at LR3 on cerebral glucose metabolism in spontaneously hypertensive rats (SHRs).
We used 18F-2-fluoro-deoxy-D-glucose positron emission tomography (18F-FDG-PET) to examine the effects of acupuncture at LR3 on cerebral glucose metabolism in SHRs.
SHRs were randomly allocated to receive no treatment (SHR group), needling at LR3 (SHR + LR3 group), or sham needling (SHR + sham group).
Rats received 10 min acupuncture once per day for 7 days and were compared to normotensive Wistar Kyoto (WKY) rats.
Blood pressure (BP) measurement and PET were performed after the first needling and the 7-day treatment period.
BP was lower in the SHR + LR3 group compared to the other SHR groups between 30 and 60 min after the first needling and at 24 and 48 h after the 7-day treatment period.
Glucose metabolism in the motor, sensory, and visual cortices was decreased in SHR group compared to WKY group.
Needling at LR3 was associated with decreased glucose metabolism in the dorsal thalamus, thalamus, and hypothalamus and with increased metabolism in the cerebellar anterior and posterior lobes, medulla oblongata, and sensory cortex compared to the SHR group.
These findings suggest that LR3 acupuncture improves hypertension through a mechanism involving altered brain activation in SHRs.
American Psychological Association (APA)
Li, Jing& Wang, Yumei& He, Kejie& Peng, Chong& Wu, Peilong& Li, Chenyun…[et al.]. 2018. Effect of Acupuncture at LR3 on Cerebral Glucose Metabolism in a Rat Model of Hypertension: A 18F-FDG-PET Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1155599
Modern Language Association (MLA)
Li, Jing…[et al.]. Effect of Acupuncture at LR3 on Cerebral Glucose Metabolism in a Rat Model of Hypertension: A 18F-FDG-PET Study. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1155599
American Medical Association (AMA)
Li, Jing& Wang, Yumei& He, Kejie& Peng, Chong& Wu, Peilong& Li, Chenyun…[et al.]. Effect of Acupuncture at LR3 on Cerebral Glucose Metabolism in a Rat Model of Hypertension: A 18F-FDG-PET Study. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1155599
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155599