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Antimicrobial and Alpha-Amylase Inhibitory Activities of Organic Extracts of Selected Sri Lankan Bryophytes
Joint Authors
Kirisanth, Annalingam
Nafas, M. N. M.
Dissanayake, Ranga K.
Wijayabandara, Jayantha
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Medicinal plants have been the main focus of natural product research.
However, recent research has revealed that lower plants including bryophytes are also a major resource of biologically active compounds with novel structures.
Sri Lanka is considered as a biodiversity hotspot with a higher degree of endemism flora including bryophytes.
In this study, different species of bryophytes were investigated for their antimicrobial and alpha-amylase inhibitory activities.
The air-dried plant materials of 6 different bryophyte species, Marchantia sp., Fissidens sp., Plagiochila sp., Sematophyllum demissum, Hypnum cupressiforme, and Calymperes motley, were subjected to sequential cold extraction with 3 different organic solvents.
All three types of organic crude extracts were subjected to screening of antimicrobial bioassays using the disc-diffusion method against 3 bacterial strains and 1 fungal strain.
According to the results obtained, 6 extracts out of 18 showed antibacterial activity for tested Gram-positive bacteria and 1 active against Gram-negative bacteria.
Two extracts showed activity against the pathogenic fungus strain.
Extracts from some plants were active against tested bacterial as well as fungal species.
TLC-based bioautographic study was carried out to identify the corresponding active bands which is useful for active compound isolation.
Furthermore, the ethyl acetate extracts were subjected to evaluate alpha-amylase inhibitory activity where three extracts out of six extracts showed moderate inhibitory activity for alpha-amylase with IC50 ranging 8–30%.
American Psychological Association (APA)
Kirisanth, Annalingam& Nafas, M. N. M.& Dissanayake, Ranga K.& Wijayabandara, Jayantha. 2020. Antimicrobial and Alpha-Amylase Inhibitory Activities of Organic Extracts of Selected Sri Lankan Bryophytes. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1155732
Modern Language Association (MLA)
Kirisanth, Annalingam…[et al.]. Antimicrobial and Alpha-Amylase Inhibitory Activities of Organic Extracts of Selected Sri Lankan Bryophytes. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1155732
American Medical Association (AMA)
Kirisanth, Annalingam& Nafas, M. N. M.& Dissanayake, Ranga K.& Wijayabandara, Jayantha. Antimicrobial and Alpha-Amylase Inhibitory Activities of Organic Extracts of Selected Sri Lankan Bryophytes. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1155732
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155732