Use of Jianpi Jiedu Herbs in Patients with Advanced Colorectal Cancer: A Systematic Review and Meta-Analysis
Joint Authors
Peng, Weijun
Sheng, Chenxia
Mao, Dan
Zhang, Shaofan
Zhang, Sifang
Lin, Fengxia
Shi, Li
Ding, Chenchen
Lei, Caiyun
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-29
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Objective.
To systematically review the effect of invigorating Pi and detoxification (Jianpi Jiedu, (JPJD)) herbs in advanced colorectal cancer (CRC) patients receiving chemotherapy.
Methods.
Three English and four Chinese databases were searched.
Literature was screened by EndNote X7 and data were analyzed by RevMan 5.2.
Results.
This review comprised 12 randomized clinical studies of 701 patients.
The results showed that JPJD herbs improved the therapeutic effect on Chinese medicine symptoms [risk ratio (RR) = 1.59; 95% confidence interval (CI): 1.35~1.88] and Karnofsky performance score [RR = 2.07; 95% CI: 1.52~2.82] for advanced CRC patients receiving chemotherapy, lowered the Chinese medicine symptoms’ score [weighted mean difference = −2.44; 95% CI: −3.23~−1.64], reduced the incidence of nausea and vomiting [RR = 0.23; 95% CI: 0.11~0.49], improved platelet at toxicity grades III-IV [odds ratio = 0.29; 95% CI: 0.12~0.74] and I–IV [RR = 0.65; 95% CI: 0.51~0.82], and improved white blood cell at toxicity grades III-IV [RR = 0.37; 95% CI: 0.23~0.58] and I–IV [RR = 0.69; 95% CI: 0.60~0.79].
However, the results showed no significant effect on tumor response.
Conclusion.
JPJD herbs can improve quality of life, relieve symptoms, and reduce adverse events of advanced CRC patients receiving chemotherapy.
American Psychological Association (APA)
Zhang, Shaofan& Shi, Li& Mao, Dan& Peng, Weijun& Sheng, Chenxia& Ding, Chenchen…[et al.]. 2018. Use of Jianpi Jiedu Herbs in Patients with Advanced Colorectal Cancer: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1155794
Modern Language Association (MLA)
Zhang, Shaofan…[et al.]. Use of Jianpi Jiedu Herbs in Patients with Advanced Colorectal Cancer: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1155794
American Medical Association (AMA)
Zhang, Shaofan& Shi, Li& Mao, Dan& Peng, Weijun& Sheng, Chenxia& Ding, Chenchen…[et al.]. Use of Jianpi Jiedu Herbs in Patients with Advanced Colorectal Cancer: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1155794
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155794