Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats
Joint Authors
Karim, Nurul
Tanvir, E. M.
Alam, Fahmida
Khalil, Md. Ibrahim
Rahman, M. Abdur
Saha, Moumoni
Hossen, Md. Sakib
Ali, Md. Yousuf
Bhoumik, Nikhil Chandra
Billah Prince, Md. Maruf
Paul, Sudip
Chowdhury, Muhammed Alamgir Zaman
Gan, Siew Hua
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-15
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The current study aimed to investigate the ameliorative effects of two types of mushrooms, Ganoderma lucidum (GL) and Auricularia polytricha (AP), against carbofuran- (CF) induced toxicity in rats.
Male Wistar rats (n=42) were divided into six equal groups.
The rats in the negative control group received oral administration of CF at 1 mg/kg with the normal diet for 28 days.
The treatment groups received oral administration of ethanolic extract of GL or AP at 100 mg/kg followed by coadministration of CF at 1 mg/kg with the normal diet for the same experimental period, respectively.
In the CF alone treated group, there were significant decreases in the erythrocytic and thrombocytic indices but increases in the concentrations of the total leukocytes, including the agranulocytes.
A significant increase in all of the liver function biomarkers except albumin, in lipid profiles except high-density lipoprotein, and in the kidney function markers occurred in the negative control group compared to the rats of the normal control and positive control groups.
The coadministration of mushroom extracts significantly ameliorated the toxic effects of the CF.
The GL mushroom extract was more efficacious than that of the AP mushroom, possibly due to the presence of high levels of phenolic compounds and other antioxidants in the GL mushroom.
American Psychological Association (APA)
Hossen, Md. Sakib& Billah Prince, Md. Maruf& Tanvir, E. M.& Chowdhury, Muhammed Alamgir Zaman& Rahman, M. Abdur& Alam, Fahmida…[et al.]. 2018. Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1155823
Modern Language Association (MLA)
Hossen, Md. Sakib…[et al.]. Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1155823
American Medical Association (AMA)
Hossen, Md. Sakib& Billah Prince, Md. Maruf& Tanvir, E. M.& Chowdhury, Muhammed Alamgir Zaman& Rahman, M. Abdur& Alam, Fahmida…[et al.]. Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1155823
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155823