Identification of the Constituents of Percutaneous Absorption from Duhaldea nervosa Based on UHPLC-Q-Exactive Orbitrap MS and Microdialysis Technique
Joint Authors
Liu, Lianghong
Zhu, Lian
Gong, Kaiyan
Zhi, Xinjun
Guan, Ying
Cai, Wei
Source
International Journal of Analytical Chemistry
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-11
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Duhaldea nervosa (D.
nervosa) has been used for treatment of bone fracture by external use.
Thus, the percutaneous absorption was crucial to the effect of D.
nervosa, especially the constituents of percutaneous absorption.
However, the constituents in vivo were never investigated to date.
In this study, an efficient method was developed for the identification of constituents of percutaneous absorption using UHPLC-Q-Exactive Orbitrap MS and microdialysis technique.
A total of 20 constituents including 15 chlorogenic acid analogues, 3 amino acids, and 2 organic acids were unambiguously or tentatively identified based on high-resolution mass data including MS and MS2, chromatography retention time, and bibliography data.
To the best of our knowledge, this is the first study to report the constituents of percutaneous absorption from D.
nervosa, which will be very helpful for understanding the bioactive compounds and quality control.
American Psychological Association (APA)
Liu, Lianghong& Zhu, Lian& Gong, Kaiyan& Zhi, Xinjun& Guan, Ying& Cai, Wei. 2019. Identification of the Constituents of Percutaneous Absorption from Duhaldea nervosa Based on UHPLC-Q-Exactive Orbitrap MS and Microdialysis Technique. International Journal of Analytical Chemistry،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1155988
Modern Language Association (MLA)
Liu, Lianghong…[et al.]. Identification of the Constituents of Percutaneous Absorption from Duhaldea nervosa Based on UHPLC-Q-Exactive Orbitrap MS and Microdialysis Technique. International Journal of Analytical Chemistry No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1155988
American Medical Association (AMA)
Liu, Lianghong& Zhu, Lian& Gong, Kaiyan& Zhi, Xinjun& Guan, Ying& Cai, Wei. Identification of the Constituents of Percutaneous Absorption from Duhaldea nervosa Based on UHPLC-Q-Exactive Orbitrap MS and Microdialysis Technique. International Journal of Analytical Chemistry. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1155988
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155988