![](/images/graphics-bg.png)
Evaluation of the In Vitro and In Vivo Antioxidant Potentials of Sudarshana Powder
Joint Authors
Perera, Pathirage Kamal
Weerakoon, Weerakoon Achchige Selvi Saroja
Gunasekera, Dulani
Suresh, Thusharie Sugandhika
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Sudarshana powder (SP) is one of the most effective Ayurveda powder preparations for paediatric febrile conditions.
The objective of the present study was to evaluate the in vitro and in vivo antioxidant potentials of SP.
The in vitro antioxidant effects were evaluated using ABTS radical cation decolourization assay where the TROLOX equivalent antioxidant capacity (TEAC) was determined.
The in vivo antioxidant activity of SP was determined in Wistar rats using the Lipid Peroxidation (LPO) assay in serum.
The in vitro assay was referred to as the TROLOX equivalent antioxidant capacity (TEAC) assay.
For the in vivo assay, animals were dosed for 21 consecutive days and blood was drawn to evaluate the MDA level.
The in vitro antioxidant activity of 0.5 μg of SP was equivalent to 14.45 μg of standard TROLOX.
The percentage inhibition against the radical formation was 50.93±0.53%.
The SP showed a statistically significant (p<0.01) decrease in the serum level of thiobarbituric acid-reactive substance in the test rats when compared with the control group.
These findings suggest that the SP possesses potent antioxidant activity which may be responsible for some of its reported bioactivities.
American Psychological Association (APA)
Weerakoon, Weerakoon Achchige Selvi Saroja& Perera, Pathirage Kamal& Gunasekera, Dulani& Suresh, Thusharie Sugandhika. 2018. Evaluation of the In Vitro and In Vivo Antioxidant Potentials of Sudarshana Powder. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1156005
Modern Language Association (MLA)
Weerakoon, Weerakoon Achchige Selvi Saroja…[et al.]. Evaluation of the In Vitro and In Vivo Antioxidant Potentials of Sudarshana Powder. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1156005
American Medical Association (AMA)
Weerakoon, Weerakoon Achchige Selvi Saroja& Perera, Pathirage Kamal& Gunasekera, Dulani& Suresh, Thusharie Sugandhika. Evaluation of the In Vitro and In Vivo Antioxidant Potentials of Sudarshana Powder. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1156005
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156005