The Efficacy and Safety of Simple-Needling Therapy for Treating Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Joint Authors
Xuan, Yichen
Huang, Hui
Huang, Yiyong
Liu, Duanyong
Hu, Xiuwu
Geng, Lele
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-13
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Clinical investigators have found that the use of needling in the treatment of ankylosing spondylitis (AS) has a good clinical application prospect in recent years.
However, these studies were insufficient to provide evidence for the efficacy and safety of simple-needling for AS.
So, we performed a systematic review and meta-analysis to evaluate the efficacy and safety of simple-needling for treating AS.
Methods.
We searched the PubMed, Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Database (CBM), Wangfang database (Wanfang), Chinese Science and Technology Periodical Database (VIP), and any other gray literature sources for randomized controlled trials (RCTs) that used simple-needling to treat AS before June 2019 with the language restriction of Chinese and English.
Researchers evaluated the retrieved literature studies and extracted valid data according to relevant requirements and used RevMan5.3 software for meta-analysis.
Results.
A total of 10 studies were included, all of which were Chinese literature studies, involving 729 patients.
Compared with the control groups, simple-needling groups had a better effect on the clinical effective rate (RR = 1.20, 95% CI (1.11, 1.29), P<0.00001), TCM syndrome score (MD = −5.26, 95% CI (−5.99, −4.53), P<0.00001), symptom score (MD = −8.08, 95% CI (−10.18, −5.97), P<0.00001), and Schober test outcome (MD = 0.39, 95% CI (0.15, 0.64), P=0.002).
Sensibility analysis was based on the leave-one-out cross-validation procedure, and the results showed no significant changes.
Most studies did not describe adverse reactions.
The funnel plot suggested publication bias on clinical effectiveness.
Conclusions.
This systematic review and meta-analysis demonstrated that simple-needling was effective as an intervention for AS.
However, due to the low quality of the methodology of included studies, the designs of clinical trials were not rigorously standardized.
Therefore, it is necessary to carry out multiquality RCTs for verification.
American Psychological Association (APA)
Xuan, Yichen& Huang, Hui& Huang, Yiyong& Liu, Duanyong& Hu, Xiuwu& Geng, Lele. 2020. The Efficacy and Safety of Simple-Needling Therapy for Treating Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1156087
Modern Language Association (MLA)
Xuan, Yichen…[et al.]. The Efficacy and Safety of Simple-Needling Therapy for Treating Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1156087
American Medical Association (AMA)
Xuan, Yichen& Huang, Hui& Huang, Yiyong& Liu, Duanyong& Hu, Xiuwu& Geng, Lele. The Efficacy and Safety of Simple-Needling Therapy for Treating Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1156087
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156087