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Antiulcer Effect of Honey in Nonsteroidal Anti-Inflammatory Drugs Induced Gastric Ulcer Model in Rats: A Systematic Review
Joint Authors
Fazalda, Annuar
Quraisiah, Adam
Nur Azlina, Mohd Fahami
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-15
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
Peptic ulcer is a basic term for ulcers on the lower oesophagus, stomach, or jejunum.
The specific term for ulcer in the stomach is gastric ulcer.
The extensive use of honey around the globe helps researchers to study the usefulness of honey.
Many studies had already been conducted and proved the effectiveness of honey in treating gastric ulcer.
Methods.
A systematic review of the literature was conducted to identify relevant studies on honey used as an alternative treatment of gastric ulcer cause by NSAIDs.
A comprehensive search was conducted in Medline, SCOPUS, and Ebscohost.
The main criteria used were articles published in English and using NSAIDs-induced gastric ulcer in rat’s model and those reporting the effectiveness of honey.
Results.
Articles published between 2001 and 2014 were identified to be relevant in studies related to the inclusion criteria.
The literature search found 30 potential and closely related articles in this review, but only 5 articles were taken which meet the criteria needed to be fulfilled.
Conclusions.
All studies in this review reported the efficacy of honey for gastric ulcer based on its antioxidant and cytoprotective activities.
Most of the studies conducted used different types of honey at various doses on rats.
Future studies should be conducted to identify the appropriate dose for humans to achieve similar gastroprotective effects.
American Psychological Association (APA)
Fazalda, Annuar& Quraisiah, Adam& Nur Azlina, Mohd Fahami. 2018. Antiulcer Effect of Honey in Nonsteroidal Anti-Inflammatory Drugs Induced Gastric Ulcer Model in Rats: A Systematic Review. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156227
Modern Language Association (MLA)
Fazalda, Annuar…[et al.]. Antiulcer Effect of Honey in Nonsteroidal Anti-Inflammatory Drugs Induced Gastric Ulcer Model in Rats: A Systematic Review. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1156227
American Medical Association (AMA)
Fazalda, Annuar& Quraisiah, Adam& Nur Azlina, Mohd Fahami. Antiulcer Effect of Honey in Nonsteroidal Anti-Inflammatory Drugs Induced Gastric Ulcer Model in Rats: A Systematic Review. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156227
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156227