The Comprehensive Therapy of Electroacupuncture Promotes Regeneration of Nerve Fibers and Motor Function Recovery in Rats after Spinal Cord Injury
Joint Authors
Wang, Fuchun
Li, Yi-Fan
Li, Tie
Zhang, Da-Wei
Xue, Hui
Chen, Dong
Li, Chen
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The present study aimed to evaluate the role of the combination treatment of methylprednisolone (MP) and electroacupuncture (EA) in regeneration of nerve fibers and functional recovery in rats with spinal cord injury (SCI).
Female Wistar rats were used for an SCI model by using a weight-drop hammer at levels T10 (spinal cord segment corresponding to the 10th thoracic vertebra).
Four groups received different treatments for the study: SCI control, MP, MP and EA, and Sham.
The growth of nerve fibers was examined by counting fluorescein positive nerve fibers.
The motor functional recovery was evaluated by Basso, Beattie, Bresnahan (BBB) score, and electrophysiology analysis.
We found that, compared to MP groups, there were more well-oriented and paralleled fluorescein positive nerve fibers in MP and EA group.
Both latencies and amplitudes of the Motor Evoked Potential (MEP) in the combination therapy of MP and EA were higher than MP group.
Additionally, recovered hindlimb movements were sustained in most rats in the MP and EA group.
Our study indicated that combination therapies could become a powerful treatment for SCI in rats.
American Psychological Association (APA)
Li, Yi-Fan& Li, Tie& Zhang, Da-Wei& Xue, Hui& Chen, Dong& Li, Chen…[et al.]. 2018. The Comprehensive Therapy of Electroacupuncture Promotes Regeneration of Nerve Fibers and Motor Function Recovery in Rats after Spinal Cord Injury. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1156235
Modern Language Association (MLA)
Li, Yi-Fan…[et al.]. The Comprehensive Therapy of Electroacupuncture Promotes Regeneration of Nerve Fibers and Motor Function Recovery in Rats after Spinal Cord Injury. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1156235
American Medical Association (AMA)
Li, Yi-Fan& Li, Tie& Zhang, Da-Wei& Xue, Hui& Chen, Dong& Li, Chen…[et al.]. The Comprehensive Therapy of Electroacupuncture Promotes Regeneration of Nerve Fibers and Motor Function Recovery in Rats after Spinal Cord Injury. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1156235
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156235