Diagnostic Value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Crohn’s Disease
Joint Authors
Li, Jin
Feng, Jue-Rong
Qiu, Xiao
Wang, Fan
Chen, Peng-Fei
Gao, Qian
Peng, Ya-Nan
Lin, Xue
Liu, Qing
Liu, Jing
Zhao, Qiu
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The aim of this study is to investigate the diagnostic efficacy of neutrophil-to-lymphocyte ratio (NLR), neutrophil-to-monocyte ratio (NMR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR) in patients with Crohn’s disease (CD) and non-CD controls.
These ratios were all derived from complete blood counts.
Two hundred and six participants including CD inpatients and non-CD controls were retrospectively enrolled.
We found statistically higher NLR and PLR and lower LMR in CD patients than in non-CD controls (all P<0.01).
However, NMR was not different between the two groups (P=0.18).
In addition, NLR, PLR, and LMR were associated with CRP and ESR.
Optimal cutoffs for NLR and PLR were 2.72 (sensitivity: 68.3%, specificity: 75.9%, and overall accuracy: 70.1%) and 132.88 (sensitivity: 76.7%, specificity: 84.8%, and overall accuracy: 80.8%), respectively.
In conclusion, the NLR and PLR might be effective, readily available, and low-cost biomarkers for differentiating CD patients from non-CD controls.
American Psychological Association (APA)
Feng, Jue-Rong& Qiu, Xiao& Wang, Fan& Chen, Peng-Fei& Gao, Qian& Peng, Ya-Nan…[et al.]. 2017. Diagnostic Value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Crohn’s Disease. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1156330
Modern Language Association (MLA)
Feng, Jue-Rong…[et al.]. Diagnostic Value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Crohn’s Disease. Gastroenterology Research and Practice No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1156330
American Medical Association (AMA)
Feng, Jue-Rong& Qiu, Xiao& Wang, Fan& Chen, Peng-Fei& Gao, Qian& Peng, Ya-Nan…[et al.]. Diagnostic Value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Crohn’s Disease. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1156330
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156330