Comparative Efficacy of Chinese Herbal Injections for Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Bayesian Network Meta-Analysis of Randomized Controlled Trials
Joint Authors
Zhao, Yi
Liu, Xinkui
Wu, Jiarui
Wang, Kaihuan
Zhang, Xiaomeng
Duan, Xiaojiao
Zhang, Dan
Huang, Xingyue
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-17
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Introduction.
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) imposes a huge economic burden on healthcare systems worldwide.
Chinese herbal injections (CHIs) are widely used to treat AECOPD.
In this study, we examined the efficacy of CHIs in the treatment of AECOPD using a network meta-analysis (NMA).
Methods.
Literature search was conducted from electronic databases of randomized controlled trials (RCTs) on CHIs plus Western medicine (WM) versus WM.
WinBUGS 1.4.3 and STATA 12.0 were adopted to compute calculations and prepare graphs, respectively.
Results.
We included 155 RCTs with 13,218 patients.
The results revealed that Danhong injection (DH) + WM had the greatest therapeutic potential in terms of rate of clinical efficacy (RCE).
In addition, in comprehensively improving RCE and FEV1%, and RCE and C-reactive protein, Huangqi injection (HQ) +WM was associated with preferable effects.
Similarly, Xixinnao injection + WM, Reduning injection (RDN) +WM, and HQ+WM had a favorable effect on RCE and PaO2.
The effect of RDN+WM was favorable in all outcomes except RCE.
The safety of CHIs needs to be further assessed.
Conclusions.
Based on this NMA, DH+WM, HQ+WM, and RDN+WM were potential optimal therapies in AECOPD and their safety should be strictly monitored.
American Psychological Association (APA)
Duan, Xiaojiao& Wu, Jiarui& Huang, Xingyue& Wang, Kaihuan& Zhao, Yi& Zhang, Dan…[et al.]. 2018. Comparative Efficacy of Chinese Herbal Injections for Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Bayesian Network Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1156345
Modern Language Association (MLA)
Duan, Xiaojiao…[et al.]. Comparative Efficacy of Chinese Herbal Injections for Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Bayesian Network Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1156345
American Medical Association (AMA)
Duan, Xiaojiao& Wu, Jiarui& Huang, Xingyue& Wang, Kaihuan& Zhao, Yi& Zhang, Dan…[et al.]. Comparative Efficacy of Chinese Herbal Injections for Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Bayesian Network Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1156345
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156345