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Safety and Effectiveness of Endoscopist-Directed Nurse-Administered Sedation during Gastric Endoscopic Submucosal Dissection
Joint Authors
Cho, Yong Suk
Shin, Sang youn
Hwang, Changhyeok
Seo, Jeonghun
Choi, Jong Won
Park, Byung Kyu
Won, Sun Young
Lee, Chun Kyon
Lee, Yong Kang
Jeon, Han Ho
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background and Aims.
Endoscopic submucosal dissection (ESD) is routinely performed in treating gastric neoplasia and requires long-term higher levels of sedation.
Endoscopist-directed nurse-administered sedation (EDNAS) has not been well studied in ESD.
This study aimed to evaluate the safety and effectiveness of EDNAS for ESD.
Methods.
Patients treated with ESD for gastric tumors between 2013 and 2015 were retrospectively collected.
Patients were divided into a midazolam-treated group (M group) and a midazolam plus propofol-treated group (MP group).
Clinical outcome, safety, effectiveness, adverse events of ESD, and adverse events of sedation were analyzed.
Results.
Of 209 collected patients, 83 were in the M group and 126 were in the MP group.
Of all patients, 67 patients had the circulatory adverse event during the ESD procedure.
Sedation method was the only significant risk factor (M versus MP: 2.17 (1.14–4.15), p=0.019).
In analysis of MP subgroups, 47 patients suffered an adverse event from sedation, and current smoking was the only significant association factor for adverse event (0.15 (0.03–0.68), p=0.014).
Conclusions.
In performing ESD, the effect of sedation is reduced in smoking patients.
EDNAS may be acceptable for ESD under careful monitoring of vital sign and oxygen saturation.
American Psychological Association (APA)
Cho, Yong Suk& Shin, Sang youn& Hwang, Changhyeok& Seo, Jeonghun& Choi, Jong Won& Park, Byung Kyu…[et al.]. 2017. Safety and Effectiveness of Endoscopist-Directed Nurse-Administered Sedation during Gastric Endoscopic Submucosal Dissection. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1156404
Modern Language Association (MLA)
Cho, Yong Suk…[et al.]. Safety and Effectiveness of Endoscopist-Directed Nurse-Administered Sedation during Gastric Endoscopic Submucosal Dissection. Gastroenterology Research and Practice No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1156404
American Medical Association (AMA)
Cho, Yong Suk& Shin, Sang youn& Hwang, Changhyeok& Seo, Jeonghun& Choi, Jong Won& Park, Byung Kyu…[et al.]. Safety and Effectiveness of Endoscopist-Directed Nurse-Administered Sedation during Gastric Endoscopic Submucosal Dissection. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1156404
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156404