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An Insight into Ginsenoside Metabolite Compound K as a Potential Tool for Skin Disorder
Joint Authors
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Ginsenosides are the major bioactive natural compounds derived from Panax ginseng.
Several studies report the pharmaceutical benefits of several ginsenosides, including antidementia, antitumor, and anti-inflammatory activity.
Biotransformations by gut microbiome contribute to the biological function of these ginsenosides.
After ingestion ginsenosides are hydrolyzed to Rg2, Rg3, compound K, and others by human gut flora.
Compound K is considered the representative active metabolite after oral administration of ginseng or ginsenosides.
Various studies report the diverse biological functions of compound K, such as antitumor, antidiabetic, antiallergic, and anti-inflammatory activity.
Recent clinical trial and in vitro studies demonstrate the antiaging activities of ginsenosides in human skin.
Ginsenosides have been considered as an important natural dermatological agent.
In this review, we will cover the modern tools and techniques to understand biotransformation and delivery of compound K.
Also the biological function of compound K on skin disorder and its potential dermatological application will be discussed.
American Psychological Association (APA)
Kim, En Hyung& Kim, Wonnam. 2018. An Insight into Ginsenoside Metabolite Compound K as a Potential Tool for Skin Disorder. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1156408
Modern Language Association (MLA)
Kim, En Hyung& Kim, Wonnam. An Insight into Ginsenoside Metabolite Compound K as a Potential Tool for Skin Disorder. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1156408
American Medical Association (AMA)
Kim, En Hyung& Kim, Wonnam. An Insight into Ginsenoside Metabolite Compound K as a Potential Tool for Skin Disorder. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1156408
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156408