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Prognostic Factors Affecting Long-Term Survival after Resection for Noncolorectal, Nonneuroendocrine, and Nonsarcoma Liver Metastases
Joint Authors
Romano, Fabrizio
Gianotti, Luca
Pinotti, Enrico
Sandini, Marta
Nespoli, Luca
Uggeri, Fabio
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aim.
To evaluate feasibility and long-term outcome after hepatic resection for noncolorectal, nonneuroendocrine, and nonsarcoma (NCNNNS) liver metastases in a single center.
Methods.
We retrospectively reviewed our experience on patients who underwent surgery for NCNNNS liver metastases from 1995 to 2015.
Patient baseline characteristics, tumor features, treatment options, and postoperative outcome were retrieved.
Results.
We included 47 patients.
The overall 5-year survival (OS) rate after hepatectomy was 27.6%, with a median survival of 21 months.
Overall survival was significantly longer for patients operated for nongastrointestinal liver metastases when compared with gastrointestinal (41 versus 10 months; p=0.027).
OS was significantly worse in patients with synchronous metastases than in those with metachronous disease (10 versus 22 months; p=0.021).
The occurrence of major postoperative complication negatively affected long-term prognosis (OS 23.5 versus 9.0 months; p=0.028).
Preoperative tumor characteristics (number and size of the lesions), intraoperative features (extension of resection, need for transfusions, and Pringle’s maneuver), and R0 at pathology were not associated with differences in overall survival.
Conclusion.
Liver resection represents a possible curative option for patients with NCNNNS metastases.
The origin of the primary tumor and the timing of metastases presentation may help clinicians to better select which patients could take advantages from surgical intervention.
American Psychological Association (APA)
Uggeri, Fabio& Pinotti, Enrico& Sandini, Marta& Nespoli, Luca& Gianotti, Luca& Romano, Fabrizio. 2017. Prognostic Factors Affecting Long-Term Survival after Resection for Noncolorectal, Nonneuroendocrine, and Nonsarcoma Liver Metastases. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1156453
Modern Language Association (MLA)
Uggeri, Fabio…[et al.]. Prognostic Factors Affecting Long-Term Survival after Resection for Noncolorectal, Nonneuroendocrine, and Nonsarcoma Liver Metastases. Gastroenterology Research and Practice No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1156453
American Medical Association (AMA)
Uggeri, Fabio& Pinotti, Enrico& Sandini, Marta& Nespoli, Luca& Gianotti, Luca& Romano, Fabrizio. Prognostic Factors Affecting Long-Term Survival after Resection for Noncolorectal, Nonneuroendocrine, and Nonsarcoma Liver Metastases. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1156453
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156453