Hydroxysafflor Yellow A: A Promising Therapeutic Agent for a Broad Spectrum of Diseases

Joint Authors

Feng, Wu-wen
Peng, Cheng
Ao, Hui

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-17, 17 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-09-25

Country of Publication

Egypt

No. of Pages

17

Main Subjects

Medicine

Abstract EN

Hydroxysafflor yellow A (HSYA) is one of the major bioactive and water-soluble compounds isolated from Carthami Flos, the flower of safflower (Carthamus tinctorius L.).

As a natural pigment with favorable medical use, HSYA has gained extensive attention due to broad and effective pharmacological activities since first isolation in 1993.

In clinic, the safflor yellow injection which mainly contains about 80% HSYA was approved by the China State Food and Drug Administration and used to treat cardiac diseases such as angina pectoris.

In basic pharmacology, HSYA has been proved to exhibit a broad spectrum of biological effects that include, but not limited to, cardiovascular effect, neuroprotection, liver and lung protection, antitumor activity, metabolism regulation, and endothelium cell protection.

Although a great number of studies have been carried out to prove the pharmacological effects and corresponding mechanisms of HYSA, a systemic review of HYSA has not yet been seen.

Here, we provide a comprehensive summarization of the pharmacological effects of HYSA.

Together with special attention to mechanisms of actions, this review can serve as the basis for further researches and developments of this medicinal compound.

American Psychological Association (APA)

Ao, Hui& Feng, Wu-wen& Peng, Cheng. 2018. Hydroxysafflor Yellow A: A Promising Therapeutic Agent for a Broad Spectrum of Diseases. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1156480

Modern Language Association (MLA)

Ao, Hui…[et al.]. Hydroxysafflor Yellow A: A Promising Therapeutic Agent for a Broad Spectrum of Diseases. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-17.
https://search.emarefa.net/detail/BIM-1156480

American Medical Association (AMA)

Ao, Hui& Feng, Wu-wen& Peng, Cheng. Hydroxysafflor Yellow A: A Promising Therapeutic Agent for a Broad Spectrum of Diseases. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1156480

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1156480