Helicobacter pylori Infection Is Associated with Type 2 Diabetes, Not Type 1 Diabetes: An Updated Meta-Analysis
Joint Authors
Li, Jun-Zhen
Li, Jie-Yao
Wu, Ting-Feng
Xu, Ji-Hao
Huang, Can-Ze
Cheng, Di
Chen, Qi-Kui
Yu, Tao
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-13
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Background.
Extragastric manifestations of Helicobacter pylori (H.
pylori) infection have been reported in many diseases.
However, there are still controversies about whether H.
pylori infection is associated with diabetes mellitus (DM).
This study was aimed at answering the question.
Methods.
A systematic search of the literature from January 1996 to January 2016 was conducted in PubMed, Embase databases, Cochrane Library, Google Scholar, Wanfang Data, China national knowledge database, and SinoMed.
Published studies reporting H.
pylori infection in both DM and non-DM individuals were recruited.
Results.
79 studies with 57,397 individuals were included in this meta-analysis.
The prevalence of H.
pylori infection in DM group (54.9%) was significantly higher than that (47.5%) in non-DM group (OR = 1.69, P<0.001).
The difference was significant in comparison between type 2 DM group and non-DM group (OR = 2.05), but not in that between type 1 DM group and non-DM group (OR = 1.23, 95% CI: 0.77–1.96, P=0.38).
Conclusion.
Our meta-analysis suggested that there is significantly higher prevalence of H.
pylori infection in DM patients as compared to non-DM individuals.
And the difference is associated with type 2 DM but not type 1 DM.
American Psychological Association (APA)
Li, Jun-Zhen& Li, Jie-Yao& Wu, Ting-Feng& Xu, Ji-Hao& Huang, Can-Ze& Cheng, Di…[et al.]. 2017. Helicobacter pylori Infection Is Associated with Type 2 Diabetes, Not Type 1 Diabetes: An Updated Meta-Analysis. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1156481
Modern Language Association (MLA)
Li, Jun-Zhen…[et al.]. Helicobacter pylori Infection Is Associated with Type 2 Diabetes, Not Type 1 Diabetes: An Updated Meta-Analysis. Gastroenterology Research and Practice No. 2017 (2017), pp.1-15.
https://search.emarefa.net/detail/BIM-1156481
American Medical Association (AMA)
Li, Jun-Zhen& Li, Jie-Yao& Wu, Ting-Feng& Xu, Ji-Hao& Huang, Can-Ze& Cheng, Di…[et al.]. Helicobacter pylori Infection Is Associated with Type 2 Diabetes, Not Type 1 Diabetes: An Updated Meta-Analysis. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1156481
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156481