Probiotics Reduce Postoperative Infections in Patients Undergoing Colorectal Surgery: A Systematic Review and Meta-Analysis
Joint Authors
Wei, Fengxian
Zhang, Youcheng
Zhang, Yawu
Liu, Peng Cheng
Yan, Yu Ke
Ma, Yu Jing
Wang, Xiang Wen
Geng, Jie
Wang, Man Cai
Xu, Xiao Dong
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
We performed this meta-analysis to investigate the efficacy of probiotics on prevention of infection-related complications following colorectal resection.
Method.
PubMed, EMBASE, Cochrane Library, and the Web of Science were searched up to January 2016.
According to the results, only randomized controlled trials that compared the efficacy of probiotics on patients with colorectal resection were included for meta-analysis.
Results.
Nine studies including a total of 1146 patients met the criteria (556 received multistrain probiotic bacteria, 590 with non-multistrain probiotic bacteria).
The combination of multistrain probiotics was beneficial in the reduction of total infections (OR = 0.30, 95%CI: 0.15–0.61, p=0.0009), including surgical site infections (SSI) (OR = 0.48, 95%CI: 0.25–0.89, p=0.02) and nonsurgical site infections (NSSI) (OR = 0.36, 95%CI: 0.23–0.56, p<0.00001).
However, there was no significant reduction in total infections (OR = 0.74, 95%CI: 0.50–1.09, p=0.13) or SSI (OR = 0.77, 95%CI: 0.52–1.12, p=0.17) with the application of non-multistrains of probiotics.
Conclusion.
Combinations of multistrain probiotic bacteria showed promise in preventing the incidence of infections following colorectal surgery.
However, the efficacy of one or two strains of probiotics remains undetermined.
American Psychological Association (APA)
Liu, Peng Cheng& Yan, Yu Ke& Ma, Yu Jing& Wang, Xiang Wen& Geng, Jie& Wang, Man Cai…[et al.]. 2017. Probiotics Reduce Postoperative Infections in Patients Undergoing Colorectal Surgery: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156499
Modern Language Association (MLA)
Liu, Peng Cheng…[et al.]. Probiotics Reduce Postoperative Infections in Patients Undergoing Colorectal Surgery: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1156499
American Medical Association (AMA)
Liu, Peng Cheng& Yan, Yu Ke& Ma, Yu Jing& Wang, Xiang Wen& Geng, Jie& Wang, Man Cai…[et al.]. Probiotics Reduce Postoperative Infections in Patients Undergoing Colorectal Surgery: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156499
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156499