Electroacupuncture Improves Blood Pressure in SHRs by Regulating the Immune Balance between Th17 and Treg
Joint Authors
Wang, Shu
Wang, Yang
Zhang, Lili
Li, Li
Hu, Hantong
Pan, Pan
Zhang, Baoyu
Ning, Wenhua
Zhao, Mengxiong
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The present study investigated the effects of electroacupuncture on blood pressure in spontaneously hypertensive rats (SHRs) by regulating the immune balance of T helper 17 cells (Th17 cells) and regulatory T cells (Treg cells).
This study investigated the role of electroacupuncture in the immune balance of SHRs using Western blot, flow cytometry, and ELISA techniques.
Electroacupuncture significantly improved blood pressure, downregulated the expression of RORγt, and upregulated the expression of Foxp3, reduced the production of Th17 cells, promoted the production of Treg cells, reduced the secretion of IL-6 and IL-17, and increased the secretion of TGF-β1 and IL-10.
These findings suggest that electroacupuncture therapy effectively improved the systolic blood pressure of SHRs, and its mechanism may be related to promotion of the immune balance between Th17 and Treg.
American Psychological Association (APA)
Wang, Yang& Zhang, Lili& Li, Li& Hu, Hantong& Pan, Pan& Zhang, Baoyu…[et al.]. 2020. Electroacupuncture Improves Blood Pressure in SHRs by Regulating the Immune Balance between Th17 and Treg. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1156554
Modern Language Association (MLA)
Wang, Yang…[et al.]. Electroacupuncture Improves Blood Pressure in SHRs by Regulating the Immune Balance between Th17 and Treg. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1156554
American Medical Association (AMA)
Wang, Yang& Zhang, Lili& Li, Li& Hu, Hantong& Pan, Pan& Zhang, Baoyu…[et al.]. Electroacupuncture Improves Blood Pressure in SHRs by Regulating the Immune Balance between Th17 and Treg. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1156554
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156554
