Treatment of Danhong Injection Combined with Naoxintong Capsule in Acute Coronary Syndrome Patients Undergoing PCI Operation: Study for a Randomized Controlled and Double-Blind Trial

Joint Authors

Zhao, Shuai
Tang, Yong
Cai, Hairong
Liu, Weifeng
Zhang, Lieyuan
Chen, Dongjie
Chen, Bojun

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-03-07

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Medicine

Abstract EN

Objective.

This double-blind and randomized placebo-controlled trial evaluated the safety and efficacy of Danhong injection combined with Naoxintong capsule in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI).

Methods.

ACS patients scheduled to undergo PCI (n=130) were equally and randomly apportioned to either a treatment or control group.

After PCI, the treatment group received Danhong injection combined with Naoxintong capsule for 12 weeks, while the control group was given placebo.

Both groups were otherwise treated with conventional secondary prevention of coronary artery disease.

The groups were primarily evaluated for clinical efficacy and cardiovascular events.

Evaluative indicators of safety included adverse events, platelet count, and liver, renal, and blood coagulation functions.

Result.

No cardiovascular events or adverse reactions were observed in either group.

The treatment group demonstrated better signs of clinical efficacy, including left ventricular ejection fraction, higher nitric oxide levels, and lower levels of endothelin-1 (ET-1) and von Willebrand factor (VWF).

Conclusion.

ACS patients treated with Danhong injection combined with Naoxintong capsule after PCI demonstrated better improvement with regard to markers associated with atherosclerosis and adverse cardiovascular events, without apparent adverse effects.

Thus, Danhong injection combined with Naoxintong capsule was safe and effective for treating ACS patients after PCI.

American Psychological Association (APA)

Zhao, Shuai& Tang, Yong& Cai, Hairong& Liu, Weifeng& Zhang, Lieyuan& Chen, Dongjie…[et al.]. 2018. Treatment of Danhong Injection Combined with Naoxintong Capsule in Acute Coronary Syndrome Patients Undergoing PCI Operation: Study for a Randomized Controlled and Double-Blind Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1156578

Modern Language Association (MLA)

Zhao, Shuai…[et al.]. Treatment of Danhong Injection Combined with Naoxintong Capsule in Acute Coronary Syndrome Patients Undergoing PCI Operation: Study for a Randomized Controlled and Double-Blind Trial. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1156578

American Medical Association (AMA)

Zhao, Shuai& Tang, Yong& Cai, Hairong& Liu, Weifeng& Zhang, Lieyuan& Chen, Dongjie…[et al.]. Treatment of Danhong Injection Combined with Naoxintong Capsule in Acute Coronary Syndrome Patients Undergoing PCI Operation: Study for a Randomized Controlled and Double-Blind Trial. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1156578

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1156578