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Platelet Count to Spleen Diameter Ratio for the Diagnosis of Gastroesophageal Varices in Liver Cirrhosis: A Systematic Review and Meta-Analysis
Joint Authors
Ding, Xia
Deng, Han
Shen, Qian
Chen, Run-hua
Xie, Chune
Wang, Wei
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-08
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Platelet count to spleen diameter ratio (PSR) was studied extensively as a noninvasive method of diagnosis for varices.
The present study aimed to systematically assess the performance of PSR in the diagnosis of varices.
PubMed, EMBASE, and article references were searched.
The summary receiver operating characteristic curves (AUSROCs), sensitivities, specificities, positive and negative likelihood ratio, and diagnostic odds ratio were calculated.
The heterogeneity, quality, and publication bias of studies were evaluated.
Subgroup and sensitivity analyses were performed.
A total of 49 papers were included.
The AUSROCs of PSR for any varices and high-risk varices were 0.8719 and 0.8132, respectively.
The summary sensitivities of PSR for any varices and high-risk varices were 0.84 and 0.78, respectively.
The summary specificities of PSR for any varices and high-risk varices were 0.78 and 0.67, respectively.
The AUSROC of PSR for any varices at the threshold of 909 was 0.8867.
The AUSROC of PSR for any varices in viral liver cirrhosis was 0.8675.
The overall quality of studies was moderate.
Significant heterogeneity and publication bias existed in the study.
In conclusion, PSR can be used to identify varices in liver cirrhosis.
PSR had a high sensitivity in viral liver cirrhosis.
American Psychological Association (APA)
Chen, Run-hua& Deng, Han& Ding, Xia& Xie, Chune& Wang, Wei& Shen, Qian. 2017. Platelet Count to Spleen Diameter Ratio for the Diagnosis of Gastroesophageal Varices in Liver Cirrhosis: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1156599
Modern Language Association (MLA)
Chen, Run-hua…[et al.]. Platelet Count to Spleen Diameter Ratio for the Diagnosis of Gastroesophageal Varices in Liver Cirrhosis: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice No. 2017 (2017), pp.1-16.
https://search.emarefa.net/detail/BIM-1156599
American Medical Association (AMA)
Chen, Run-hua& Deng, Han& Ding, Xia& Xie, Chune& Wang, Wei& Shen, Qian. Platelet Count to Spleen Diameter Ratio for the Diagnosis of Gastroesophageal Varices in Liver Cirrhosis: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1156599
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156599