Fat-Soluble Vitamin Deficiency in Pediatric Patients with Biliary Atresia
Joint Authors
Chen, Gong
Zheng, Shan
Sun, Song
Liu, Xiao-Zhou
Shen, Zhen
Dong, Rui
Source
Gastroenterology Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To analyze the levels of fat-soluble vitamins (FSVs) in pediatric patients with biliary atresia (BA) before and after the Kasai procedure.
Methods.
Pediatric patients with obstructive jaundice were enrolled in this study.
The FSV levels and liver function before, 2 weeks after, and 1, 3, and 6 months after the Kasai procedure were measured.
Results.
FSV deficiency was more obvious in patients with BA than in patients with other cholestatic liver diseases, especially vitamin D deficiency.
25-Hydroxy vitamin D (25-(OH)D) deficiency was more pronounced in younger patients before surgery.
The 25-(OH)D level was significantly higher in patients with than without resolution of jaundice 3 months after surgery.
At 6 months after surgery, the 25-(OH)D level was abnormally high at 8.76 ng/ml in patients with unresolved jaundice.
Conclusions.
Preoperative FSV deficiency, particularly vitamin D deficiency, is common in patients with BA.
25-(OH)D deficiency is more pronounced in younger children before surgery.
Postoperative FSV deficiency was still prevalent as shown by the lower 25-(OH)D levels in patients with BA and unresolved jaundice.
This required long-term vitamin AD supplementation for pediatric patients with BA and unresolved jaundice after surgery.
American Psychological Association (APA)
Dong, Rui& Sun, Song& Liu, Xiao-Zhou& Shen, Zhen& Chen, Gong& Zheng, Shan. 2017. Fat-Soluble Vitamin Deficiency in Pediatric Patients with Biliary Atresia. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1156602
Modern Language Association (MLA)
Dong, Rui…[et al.]. Fat-Soluble Vitamin Deficiency in Pediatric Patients with Biliary Atresia. Gastroenterology Research and Practice No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1156602
American Medical Association (AMA)
Dong, Rui& Sun, Song& Liu, Xiao-Zhou& Shen, Zhen& Chen, Gong& Zheng, Shan. Fat-Soluble Vitamin Deficiency in Pediatric Patients with Biliary Atresia. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1156602
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156602