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An Herbal Medicine, Yukgunja-Tang is more Effective in a Type of Functional Dyspepsia Categorized by Facial Shape Diagnosis: A Placebo-Controlled, Double-Blind, Randomized Trial
Joint Authors
Park, Jae-Woo
Jeon, Soo Hyung
Kim, Jong Won
Lee, Jae-hyung
Lee, Jung-eun
Ha, Na-yeon
Nam, Seong-uk
Lee, Jae-hong
Kang, Changwan
Yeo, Inkwon
Kim, Jinsung
Ko, Seok-Jae
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-01
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Introduction.
Functional dyspepsia (FD) is a functional gastrointestinal disorder characterized by persistent upper dyspeptic symptoms without organic lesions.
There is no standard therapy for FD.
Yukgunja-tang (YGJT) is an herbal medicine used for treating upper gastrointestinal symptoms in Asia.
Studies on the effect of YGJT on FD have been conducted.
However, the results were inconsistent.
In Hyungsang medicine, traditional Korean medicine, FD patients are classified into bladder body (BB) or gallbladder body (GB) subtypes by the shape and angle of their faces.
Each subtype may have different characteristics, physiology, and pathology of the same disease.
YGJT is more effective for patients with BB subtype.
The three-dimensional facial shape diagnostic system (3-FSDS) was shown to be effective in diagnosing BB or GB subtypes.
This study aimed to investigate the effect of YGJT on FD patients classified using the 3-FSDS.
Materials and Methods.
The current study was a placebo-controlled, double-blinded, randomized, two-center trial.
Eligible patients were diagnosed with either BB or GB FD subtype using the 3-FSDS.
Ninety-six participants (48 BB and 48 GB subtypes) were randomly allocated to treatment or control groups in a 2:1 ratio.
YGJT or placebo was administered for eight weeks.
The primary outcome was assessed using the total dyspepsia symptom scale (TDS), while the secondary outcomes were assessed using the single dyspepsia symptom scale (SDS), proportion of responders, visual analog scale, Nepean dyspepsia index, functional dyspepsia-related quality of life, and spleen qi deficiency questionnaire.
Results and Discussion.
The result of TDS showed the superior effect of YGJT on BB over GB subtype.
The subgroup analysis of TDS and SDS scores showed the superior effect of YGJT over placebo.
Other outcome variables did not show any significant differences between groups.
Conclusion.
YGJT may be considered for FD patients diagnosed with BB subtype using 3-FSDS.
American Psychological Association (APA)
Ko, Seok-Jae& Park, Jae-Woo& Lee, Jae-hyung& Lee, Jung-eun& Ha, Na-yeon& Nam, Seong-uk…[et al.]. 2018. An Herbal Medicine, Yukgunja-Tang is more Effective in a Type of Functional Dyspepsia Categorized by Facial Shape Diagnosis: A Placebo-Controlled, Double-Blind, Randomized Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1156608
Modern Language Association (MLA)
Ko, Seok-Jae…[et al.]. An Herbal Medicine, Yukgunja-Tang is more Effective in a Type of Functional Dyspepsia Categorized by Facial Shape Diagnosis: A Placebo-Controlled, Double-Blind, Randomized Trial. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1156608
American Medical Association (AMA)
Ko, Seok-Jae& Park, Jae-Woo& Lee, Jae-hyung& Lee, Jung-eun& Ha, Na-yeon& Nam, Seong-uk…[et al.]. An Herbal Medicine, Yukgunja-Tang is more Effective in a Type of Functional Dyspepsia Categorized by Facial Shape Diagnosis: A Placebo-Controlled, Double-Blind, Randomized Trial. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1156608
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156608