Traditional Chinese Medicine for Refractory Nephrotic Syndrome: Strategies and Promising Treatments
Joint Authors
Wang, Xiao-Qin
Zhang, Yuan Clare
Wang, Lan
Tu, Yuan-Chao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-04
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Refractory nephrotic syndrome (RNS) is an immune-related kidney disease with poor clinical outcomes.
Standard treatments include corticosteroids as the initial therapy and other immunosuppressants as second-line options.
A substantial proportion of patients with RNS are resistant to or dependent on immunosuppressive drugs and often experience unremitting edema and proteinuria, cycles of remission and relapse, and/or serious adverse events due to long-term immunosuppression.
Traditional Chinese medicine has a long history of treating complicated kidney diseases and holds great potential for providing effective treatments for RNS.
This review describes the Chinese medical theories relating to the pathogenesis of RNS and discusses the strategies and treatment options using Chinese herbal medicine.
Available preclinical and clinical evidence strongly supports the integration of traditional Chinese medicine and Western medicine for improving the outcome of RNS.
Herbal medicine such as Astragalus membranaceus, Stephania tetrandra S.
Moore, and Tripterygium wilfordii Hook F can serve as the alternative therapy when patients fail to respond to immunosuppression or as the complementary therapy to improve therapeutic efficacy and reduce side effects of immunosuppressive agents.
Wuzhi capsules (Schisandra sphenanthera extract) with tacrolimus and tetrandrine with corticosteroids are two herb-drug combinations that have shown great promise and warrant further studies.
American Psychological Association (APA)
Wang, Xiao-Qin& Wang, Lan& Tu, Yuan-Chao& Zhang, Yuan Clare. 2018. Traditional Chinese Medicine for Refractory Nephrotic Syndrome: Strategies and Promising Treatments. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1156723
Modern Language Association (MLA)
Wang, Xiao-Qin…[et al.]. Traditional Chinese Medicine for Refractory Nephrotic Syndrome: Strategies and Promising Treatments. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1156723
American Medical Association (AMA)
Wang, Xiao-Qin& Wang, Lan& Tu, Yuan-Chao& Zhang, Yuan Clare. Traditional Chinese Medicine for Refractory Nephrotic Syndrome: Strategies and Promising Treatments. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1156723
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156723