Botanical and Traditional Uses and Phytochemical, Pharmacological, Pharmacokinetic, and Toxicological Characteristics of Ziziphi Spinosae Semen: A Review
Joint Authors
He, Su-Rong
Zhao, Chong-Bo
Zhang, Jing-Xia
Wang, Jing
Wu, Bo
Wu, Chun-Jie
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-10
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Abstract EN
Ziziphi Spinosae Semen (ZS, the seeds of Ziziphus jujuba Mill.
var.
spinosa (Bunge) Hu ex H.
F.
Chou) is used as a traditional Chinese medicine referred to as Suan zao ren (酸枣仁).
This paper aims to provide a systematic review of its traditional uses and its botanical, phytochemical, pharmacological, pharmacokinetic, and toxicological characteristics.
The future development and research prospects for ZS have also been discussed in detail.
To date, over 150 compounds have been identified in this plant, including terpenoids, alkaloids, flavonoids, fatty acids, volatile oils, polysaccharides, and others.
Both extracts and purified compounds have excellent biological activities, especially sedative and hypnotic effects.
Other effects include ameliorating effect of learning and memory, anti-inflammation, antioxidation, blood pressure and lipid lowering, antiaging, and antitumor effects.
Thus, this traditional Chinese medicine can be used to treat many diseases such as insomnia, forgetfulness, headaches, and dizziness.
Although many of the traditional uses of ZS are well established, the relationship between structure and function still needs to be further studied.
In order to better pave the way for research and the establishment of quality control standards for ZS, it will be very important to elucidate its pharmacological mechanisms of action and explore new clinical effects.
American Psychological Association (APA)
He, Su-Rong& Zhao, Chong-Bo& Zhang, Jing-Xia& Wang, Jing& Wu, Bo& Wu, Chun-Jie. 2020. Botanical and Traditional Uses and Phytochemical, Pharmacological, Pharmacokinetic, and Toxicological Characteristics of Ziziphi Spinosae Semen: A Review. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-21.
https://search.emarefa.net/detail/BIM-1156764
Modern Language Association (MLA)
He, Su-Rong…[et al.]. Botanical and Traditional Uses and Phytochemical, Pharmacological, Pharmacokinetic, and Toxicological Characteristics of Ziziphi Spinosae Semen: A Review. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-21.
https://search.emarefa.net/detail/BIM-1156764
American Medical Association (AMA)
He, Su-Rong& Zhao, Chong-Bo& Zhang, Jing-Xia& Wang, Jing& Wu, Bo& Wu, Chun-Jie. Botanical and Traditional Uses and Phytochemical, Pharmacological, Pharmacokinetic, and Toxicological Characteristics of Ziziphi Spinosae Semen: A Review. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-21.
https://search.emarefa.net/detail/BIM-1156764
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156764