Therapeutic Potential of Quercetin as an Antiatherosclerotic Agent in Atherosclerotic Cardiovascular Disease: A Review

Abstract EN

Atherosclerotic cardiovascular disease (ASCVD) is one of the diseases with the highest morbidity and mortality globally.

It causes a huge burden on families and caregivers and high costs for medicine and surgical interventions.

Given expensive surgeries and failures of most conventional treatments, medical community tries to find a more cost-effective cure.

Thus, attentions have been primarily focused on food or herbs.

Quercetin (Qu) extracted from food, a flavonoid component, develops potentials of alternative or complementary medicine in atherosclerosis.

Due to the wide range of health benefits, researchers have considered to apply Qu as a natural compound in therapy.

This review is aimed to identify the antiatherosclerosis functions of Qu in treating ASCVD such as anti-inflammatory, antioxidant properties, effects on endothelium-dependent vasodilation, and blood lipid-lowering.