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Ingestion of Exopolymers from Aureobasidium pullulans Reduces the Duration of Cold and Flu Symptoms: A Randomized, Placebo-Controlled Intervention Study
Joint Authors
Baek, Kyung Min
Choi, Jae-Suk
Lim, Jong Min
Do, Eunju
Park, Dong-Chan
Jung, Go-Woon
Lee, Seo-Young
Shin, Jae Wook
Cho, Hyung-Rae
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-30
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Aim.
The objective of the study was to assess the efficacy of exopolymers from Aureobasidium pullulans (EAP) on the incidence of colds and flu in healthy adults.
Methods.
We conducted a randomized, double-blind, placebo-controlled study at the onset of the influenza season.
A total of 76 subjects (30–70 years of age) were recruited from the general population.
The subjects were instructed to take one capsule per day of either EAP or a placebo for a period of 8 weeks.
The duration of cold and flu symptoms, a primary variable in assessing effectiveness, and serum cytokine levels as well as WBC counts as secondary variables were also evaluated.
Results.
EAP was associated with a statistically significant decrease in the duration of cold and flu symptoms, a primary variable in assessing effectiveness.
Although cold and flu symptom levels were not significantly different at a significance level of 5%, the cold and flu symptom levels of the EAP group were less severe compared to the placebo group.
No statistically significant changes of serum cytokine levels as well as WBC counts were observed.
Conclusion.
The results showed that EAP is a useful pharmaceutical and functional food material for preventing and treating colds and flu.
American Psychological Association (APA)
Lim, Jong Min& Do, Eunju& Park, Dong-Chan& Jung, Go-Woon& Cho, Hyung-Rae& Lee, Seo-Young…[et al.]. 2018. Ingestion of Exopolymers from Aureobasidium pullulans Reduces the Duration of Cold and Flu Symptoms: A Randomized, Placebo-Controlled Intervention Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156790
Modern Language Association (MLA)
Lim, Jong Min…[et al.]. Ingestion of Exopolymers from Aureobasidium pullulans Reduces the Duration of Cold and Flu Symptoms: A Randomized, Placebo-Controlled Intervention Study. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1156790
American Medical Association (AMA)
Lim, Jong Min& Do, Eunju& Park, Dong-Chan& Jung, Go-Woon& Cho, Hyung-Rae& Lee, Seo-Young…[et al.]. Ingestion of Exopolymers from Aureobasidium pullulans Reduces the Duration of Cold and Flu Symptoms: A Randomized, Placebo-Controlled Intervention Study. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156790
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156790