Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network

Joint Authors

Xu, Zhifang
Zhao, Xue
Ding, Shasha
Yan, Yawen
Guo, Xinmeng
Zhang, Kuo
Wang, Jiang
Li, Kai
Guo, Yi
Liu, Yangyang

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-17, 17 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-01-29

Country of Publication

Egypt

No. of Pages

17

Main Subjects

Medicine

Abstract EN

The mechanisms of acupuncture are still unclear.

In order to reveal the regulatory effect of manual acupuncture (MA) on the neuroendocrine-immune (NEI) network and identify the key signaling molecules during MA modulating NEI network, we used a rat complete Freund’s adjuvant (CFA) model to observe the analgesic and anti-inflammatory effect of MA, and, what is more, we used statistical and complex network methods to analyze the data about the expression of 55 common signaling molecules of NEI network in ST36 (Zusanli) acupoint, and serum and hind foot pad tissue.

The results indicate that MA had significant analgesic, anti-inflammatory effects on CFA rats; the key signaling molecules may play a key role during MA regulating NEI network, but further research is needed.

American Psychological Association (APA)

Zhang, Kuo& Guo, Xinmeng& Yan, Yawen& Liu, Yangyang& Xu, Zhifang& Zhao, Xue…[et al.]. 2018. Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1156849

Modern Language Association (MLA)

Zhang, Kuo…[et al.]. Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-17.
https://search.emarefa.net/detail/BIM-1156849

American Medical Association (AMA)

Zhang, Kuo& Guo, Xinmeng& Yan, Yawen& Liu, Yangyang& Xu, Zhifang& Zhao, Xue…[et al.]. Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1156849

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1156849