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Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network
Joint Authors
Xu, Zhifang
Zhao, Xue
Ding, Shasha
Yan, Yawen
Guo, Xinmeng
Zhang, Kuo
Wang, Jiang
Li, Kai
Guo, Yi
Liu, Yangyang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-29
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
The mechanisms of acupuncture are still unclear.
In order to reveal the regulatory effect of manual acupuncture (MA) on the neuroendocrine-immune (NEI) network and identify the key signaling molecules during MA modulating NEI network, we used a rat complete Freund’s adjuvant (CFA) model to observe the analgesic and anti-inflammatory effect of MA, and, what is more, we used statistical and complex network methods to analyze the data about the expression of 55 common signaling molecules of NEI network in ST36 (Zusanli) acupoint, and serum and hind foot pad tissue.
The results indicate that MA had significant analgesic, anti-inflammatory effects on CFA rats; the key signaling molecules may play a key role during MA regulating NEI network, but further research is needed.
American Psychological Association (APA)
Zhang, Kuo& Guo, Xinmeng& Yan, Yawen& Liu, Yangyang& Xu, Zhifang& Zhao, Xue…[et al.]. 2018. Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1156849
Modern Language Association (MLA)
Zhang, Kuo…[et al.]. Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-17.
https://search.emarefa.net/detail/BIM-1156849
American Medical Association (AMA)
Zhang, Kuo& Guo, Xinmeng& Yan, Yawen& Liu, Yangyang& Xu, Zhifang& Zhao, Xue…[et al.]. Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1156849
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156849