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Antioxidant Potential of Herbal Preparations and Components from Galactites elegans (All.) Nyman ex Soldano
Joint Authors
Malafronte, Nicola
Vassallo, Antonio
Tebboub, Omar
Cotugno, Roberta
Oke-Altuntas, Feyza
Bouheroum, Mohamed
D’Ambola, Massimiliano
Demirtas, Ibrahim
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Galactites is a genus of flowering plants belonging to Asteraceae family.
This genus is mainly represented by the Galactites elegans (All.) Nyman ex Soldano, the milky thistle, a plant of Mediterranean origin.
Galactites elegans is consumed as a monofloral boar thistle honey.
Chromatography separation of CHCl3 and n-BuOH extracts of aerial parts of G.
elegans led to isolation of 18 pure compounds.
Their structures were elucidated by 1D-and 2D-NMR spectroscopy and confirmed by mass spectrometry analysis.
Sinapic aldehyde, abietin, chlorogenic acid, neochlorogenic acid, 8α-hydroxypinoresinol, 9α-hydroxypinoresinol, pinoresinol, 4-ketopinoresinol, nortrachelogenin, and erythro-guaiacylglycerol-β-O-4′-dihydroconiferyl alcohol were isolated from CHCl3 extract, while luteolin 4′-O-glucuronide, naringenin-7-O-neohesperidoside, kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside, apigenin-7-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside, quercitrin, quercetin-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside, ciwujiatone, and nortrachelogenin-4,4′-di-O-β-D-glucopyranoside were obtained from n-BuOH extract.
The majority of isolated compounds displayed a significant antioxidant potential in vitro test (DPPH).
The ability of compounds to reduce the level of peroxides in control and BHP-treated Jurkat cells was studied.
The lignan derivatives were also able to reduce at 50 μM the basal level of peroxides in Jurkat cells as well as counteract peroxide increase induced by BHP treatment.
Particularly 8α-hydroxypinoresinol was the most active showing 70% of peroxide level inhibition.
American Psychological Association (APA)
Tebboub, Omar& Cotugno, Roberta& Oke-Altuntas, Feyza& Bouheroum, Mohamed& Demirtas, Ibrahim& D’Ambola, Massimiliano…[et al.]. 2018. Antioxidant Potential of Herbal Preparations and Components from Galactites elegans (All.) Nyman ex Soldano. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1156864
Modern Language Association (MLA)
Tebboub, Omar…[et al.]. Antioxidant Potential of Herbal Preparations and Components from Galactites elegans (All.) Nyman ex Soldano. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1156864
American Medical Association (AMA)
Tebboub, Omar& Cotugno, Roberta& Oke-Altuntas, Feyza& Bouheroum, Mohamed& Demirtas, Ibrahim& D’Ambola, Massimiliano…[et al.]. Antioxidant Potential of Herbal Preparations and Components from Galactites elegans (All.) Nyman ex Soldano. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1156864
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156864