Investigating the Antiproliferative and Antioxidant Properties of Pancratium maritimum L. (Amaryllidaceae) Stems, Flowers, Bulbs, and Fruits Extracts
Joint Authors
Tundis, Rosa
Leporini, Mariarosaria
Catinella, Giorgia
Bruno, Maurizio
Falco, Tiziana
Loizzo, Monica R.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Pancratium maritimum stems, flowers, bulbs, and fruits extracts were investigated for their antiproliferative and antioxidant properties.
Total phenols and total flavonoids were also determined.
The in vitro antiproliferative activity was tested against seven cancer cell lines such as C32, HeLa, MDA-MB-231, PC3, A549, MCF-7, and LNCaP by using SRB assay.
Interesting results were obtained with stems ethanol extract (ET1) against C32 cells (IC50 of 27.1 μg/mL) and fruits aqueous extract (AQ) against MCF-7 cell line (IC50 of 36.5 μg/mL).
To define the antioxidant activity, four tests such as DPPH, ABTS FRAP, and β-carotene bleaching tests were used.
The most promising ABTS scavenging capacity was observed with fruits ethanol extract (ET1) that showed an IC50 value of 6.9 μg/mL.
According to the correlation results, the phenols and flavonoids content could provide a fundamental contribution to the antioxidant and antiproliferative activity of P.
maritimum extracts.
American Psychological Association (APA)
Leporini, Mariarosaria& Catinella, Giorgia& Bruno, Maurizio& Falco, Tiziana& Tundis, Rosa& Loizzo, Monica R.. 2018. Investigating the Antiproliferative and Antioxidant Properties of Pancratium maritimum L. (Amaryllidaceae) Stems, Flowers, Bulbs, and Fruits Extracts. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1156867
Modern Language Association (MLA)
Leporini, Mariarosaria…[et al.]. Investigating the Antiproliferative and Antioxidant Properties of Pancratium maritimum L. (Amaryllidaceae) Stems, Flowers, Bulbs, and Fruits Extracts. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1156867
American Medical Association (AMA)
Leporini, Mariarosaria& Catinella, Giorgia& Bruno, Maurizio& Falco, Tiziana& Tundis, Rosa& Loizzo, Monica R.. Investigating the Antiproliferative and Antioxidant Properties of Pancratium maritimum L. (Amaryllidaceae) Stems, Flowers, Bulbs, and Fruits Extracts. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1156867
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156867