Microbial Diversity of Chronic Wound and Successful Management of Traditional Chinese Medicine
Joint Authors
Li, Fu-Lun
Li, Bin
Wu, Min-feng
Li, Yan
Guo, Dongjie
Kui, Gang
Deng, Yu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-09
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Chronic ulcer, including diabetic ulcer, varicose ulcer, and pressure ulcer, negatively affects patients’ quality of life.
As microbiology plays an important role in the mechanism of pathology for chronic wound healing, this study concentrates on microecology environment of the wound and how Traditional Chinese Medicine (TCM) regulates wound bacteria.
Method.
The study took wound samples from 35 patients and analyzed bacteria variation before and after TCM treatment by 16s rRNA sequencing.
All samples were evaluated from aspects of α-diversity, β-diversity, and Simpson’s Diversity index.
Result.
After total DNA extraction, PCR, and 16S rRNA sequencing of wound bacteria from 35 individuals, it was discovered that younger patients with shorter course of disease have a higher microbial diversity and were easier to recover from ulcers.
Additionally, gender also played a vital role in wound healing, and a significant microbial diversity existed between male and female patients.
Conclusion.
Patients with chronic ulcers achieved a positive effect after TCM treatment (skin-producing ointment).
Mechanistically, TCM helped promote wound healing by regulating the wound microbiota.
American Psychological Association (APA)
Wu, Min-feng& Li, Yan& Guo, Dongjie& Kui, Gang& Li, Bin& Deng, Yu…[et al.]. 2018. Microbial Diversity of Chronic Wound and Successful Management of Traditional Chinese Medicine. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1156900
Modern Language Association (MLA)
Wu, Min-feng…[et al.]. Microbial Diversity of Chronic Wound and Successful Management of Traditional Chinese Medicine. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1156900
American Medical Association (AMA)
Wu, Min-feng& Li, Yan& Guo, Dongjie& Kui, Gang& Li, Bin& Deng, Yu…[et al.]. Microbial Diversity of Chronic Wound and Successful Management of Traditional Chinese Medicine. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1156900
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156900