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A Prospective Randomized, Controlled, Double-Blind Trial of the Efficacy Using Centella Cream for Scar Improvement
Joint Authors
Surakunprapha, Palakorn
Jenwitheesuk, Kamonwan
Rojsanga, Porntip
Chowchuen, Bowornsilp
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-17
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
This study was performed to evaluate the efficacy of Centella asiatica extract in cream, a preparation for the prevention of scar development of the split-thickness skin graft (STSG) donor site.
Methods.
A prospective randomized, double-blind control study was performed to evaluate the efficacy of Centella cream in 30 patients who underwent a STSG operation.
Both Centella cream and placebo were applied equally to the donor site at least 2 weeks after epithelialization was completed.
A scar assessment using the Vancouver Scar Scale (VSS) was taken at 4, 8, and 12 weeks.
Results.
Of the original 30 patients, 23 patients completed evaluation.
There were significant differences in pigmentation parameter of VSS and comparative total VSS scores between 4 and 12 weeks in Centella cream group.
Conclusion.
The effect of Centella cream on scar development of a STSG operation may be attainable in terms of better pigmentation.
By means of objective measurements and longer follow-up times, Centella cream may prove to be an alternative product for hypertrophic scar amelioration.
American Psychological Association (APA)
Jenwitheesuk, Kamonwan& Rojsanga, Porntip& Chowchuen, Bowornsilp& Surakunprapha, Palakorn. 2018. A Prospective Randomized, Controlled, Double-Blind Trial of the Efficacy Using Centella Cream for Scar Improvement. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1156913
Modern Language Association (MLA)
Jenwitheesuk, Kamonwan…[et al.]. A Prospective Randomized, Controlled, Double-Blind Trial of the Efficacy Using Centella Cream for Scar Improvement. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1156913
American Medical Association (AMA)
Jenwitheesuk, Kamonwan& Rojsanga, Porntip& Chowchuen, Bowornsilp& Surakunprapha, Palakorn. A Prospective Randomized, Controlled, Double-Blind Trial of the Efficacy Using Centella Cream for Scar Improvement. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1156913
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156913