Herbal Formula Modified Buzhong-Yiqi-Tang for Functional Constipation in Adults: A Meta-Analysis of Randomized Controlled Trials
Joint Authors
He, Hongbo
Gong, Hanlin
Qin, Feng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-16
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
Herbal formula Modified Buzhong-Yiqi-Tang (MBYT) has been widely used for the treatment of functional constipation in East Asia, but its efficacy and safety are unclear.
Methods.
The study was to evaluate the efficacy and safety of MBYT for adult patients with functional constipation.
Randomized clinical trials were selected according to predefined inclusion and exclusion criteria.
Results.
In total, twenty-five randomized controlled clinical trials were included with 2089 patients.
There was evidence that MBYT treatment significantly improved the symptoms of functional constipation compared with stimulant laxatives, osmotic laxatives, and prokinetic agents.
Our results also demonstrated that, when used as an adjuvant therapy, MBYT significantly improved the symptoms of functional constipation, when compared with osmotic laxatives alone, prokinetic agents alone, and biofeedback alone.
Moreover, patients taking MBYT experienced fewer adverse events compared to the control groups.
Conclusion.
This review suggests that MBYT appears to have excellent therapeutic effect on adult patients with functional constipation and no serious side effects were identified.
However, due to overall limited quality, the therapeutic benefit of MBYT may be substantiated to a limited degree.
Better methodological quality and large controlled trials are expected to further quantify the therapeutic effect of MBYT.
American Psychological Association (APA)
Gong, Hanlin& Qin, Feng& He, Hongbo. 2018. Herbal Formula Modified Buzhong-Yiqi-Tang for Functional Constipation in Adults: A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156930
Modern Language Association (MLA)
Gong, Hanlin…[et al.]. Herbal Formula Modified Buzhong-Yiqi-Tang for Functional Constipation in Adults: A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1156930
American Medical Association (AMA)
Gong, Hanlin& Qin, Feng& He, Hongbo. Herbal Formula Modified Buzhong-Yiqi-Tang for Functional Constipation in Adults: A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156930
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156930