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Evaluation of the Healing Effects of Hypericum perforatum and Curcumin on Burn Wounds in Rats
Author
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
For centuries, medicinal plants have been extensively used in wound healing of burn injuries.
The aim of this study is to analyze comparatively the effects of curcumin and Hypericum perforatum (HP) on second-degree burn wounds in rats.
Materials and Methods.
This experimental study was conducted on 24 male Sprague-Dawley rats with second-degree burns.
The animals were randomly divided into three groups.
The burns were treated with curcumin (Group B) and Hypericum perforatum (Group C) with daily application.
Group A was considered as the control group and received no medication.
Histological parameters, reepithelization, granulation tissue formation, inflammation, and angiogenesis were assessed after the scar biopsy at the end of research.
Results.
All histological parameters of the control group showed statistically significant difference than the other groups (p<0.05).
There was no statistically significant difference between Groups B and C in terms of reepithelization and inflammation (p=0.351, p=0.067).
In the curcumin group compared with the HP group, a significant difference was observed for two parameters of fibrosis and angiogenesis (p<0.05).
Conclusion.
Both curcumin and Hypericum perforatum oil are effective in burn wound healing.
Our findings showed a better quality of healing in curcumin-treated rats.
American Psychological Association (APA)
Seyhan, Nevra. 2020. Evaluation of the Healing Effects of Hypericum perforatum and Curcumin on Burn Wounds in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1156951
Modern Language Association (MLA)
Seyhan, Nevra. Evaluation of the Healing Effects of Hypericum perforatum and Curcumin on Burn Wounds in Rats. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1156951
American Medical Association (AMA)
Seyhan, Nevra. Evaluation of the Healing Effects of Hypericum perforatum and Curcumin on Burn Wounds in Rats. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1156951
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156951