Efficacy of Bloodletting Therapy in Patients with Chronic Idiopathic Urticaria: A Randomized Control Trial
Joint Authors
Chen, Xiuhua
Meng, Fanqi
Ma, Biru
Liang, Yudan
Ouyang, Weiquan
Tang, Boyan
Quan, Xiaohong
Chen, Dacan
Li, Ying
Wang, Cong
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-30
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
To assess the efficacy of bloodletting therapy (acupoint pricking and cupping) in patients with chronic idiopathic urticaria (CIU) in a randomized, control, parallel-group trial.
Methods.
A total of 174 patients with CIU enrolled from March 2018 to October 2019 were randomized into three groups: group A treated with bloodletting therapy and ebastine, group B treated with placebo treatment (acupoint pseudopricking and cupping) and ebastine, and group C treated with ebastine only.
The intention-to-treat analysis was conducted, and the primary outcome was the effective rate of UAS7 score being reduced to 7 or below after treatment phase.
Results.
The effective rates at the end of treatment phase were different among the three groups (P<0.05), which were 73.7% in group A, 45.6% in group B, and 42.9% in group C.
Multiple analysis indicated differences between groups A and B (P<0.0125) and groups A and C (P<0.0125) and no difference between groups B and C (P>0.0125).
No severe bloodletting therapy-related adverse events were observed.
Conclusions.
In this study on patients with CIU, one month of bloodletting therapy combined with ebastine is clinically beneficial compared with placebo treatment combined with ebastine and treatment with ebastine only.
Thus, bloodletting therapy can be an effective complementary treatment in CIU.
This trial is registered with ChiCTR1800015294.
American Psychological Association (APA)
Ma, Biru& Chen, Xiuhua& Liang, Yudan& Ouyang, Weiquan& Tang, Boyan& Meng, Fanqi…[et al.]. 2020. Efficacy of Bloodletting Therapy in Patients with Chronic Idiopathic Urticaria: A Randomized Control Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1156997
Modern Language Association (MLA)
Ma, Biru…[et al.]. Efficacy of Bloodletting Therapy in Patients with Chronic Idiopathic Urticaria: A Randomized Control Trial. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1156997
American Medical Association (AMA)
Ma, Biru& Chen, Xiuhua& Liang, Yudan& Ouyang, Weiquan& Tang, Boyan& Meng, Fanqi…[et al.]. Efficacy of Bloodletting Therapy in Patients with Chronic Idiopathic Urticaria: A Randomized Control Trial. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1156997
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1156997