The Diagnostic Value of Irisin in Pediatric Patients with Acute Abdominal Pain
Joint Authors
Buyukbese Sarsu, Sevgi
Sarac, Fatma
Yucetas, Esma
Yeniocak, Selman
Sahin, Kamil
Yildirim, Dogan
Koldas, Macit
Uzun, Ozlem
Source
Emergency Medicine International
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
Diagnosis of pediatric patients presenting to the Emergency Department with acute abdominal pain is not always easy.
The purpose of this study was to investigate the effectiveness of irisin, a peptide hormone with reactivity shown in the appendix and neutrophils, in the differential diagnosis of pediatric patients with acute abdominal pain.
Methods.
162 subjects consenting to participate, including 112 patients presenting to the Pediatric Emergency and Pediatric Surgery clinics with acute abdominal pain and 50 controls, were enrolled in the study.
Blood was collected from all patients following initial examination for irisin, WBC, and CRP investigation.
Results.
Mean irisin levels in cases of acute appendicitis (AA) and perforated appendicitis (PA) were statistically significantly higher compared to nonspecific abdominal pains and the control group.
No statistically significant difference was observed in irisin levels between AA and PA cases.
WBC and CRP levels were also significantly higher in cases of AA and PA compared to nonspecific abdominal pains.
Conclusions.
Differential diagnosis of acute abdominal pains in children and deciding on surgery are a difficult and complex process.
Our study shows that irisin can be a useful biomarker in differentiating AA and PA from other acute abdominal pains in children.
American Psychological Association (APA)
Sarac, Fatma& Buyukbese Sarsu, Sevgi& Yeniocak, Selman& Sahin, Kamil& Yucetas, Esma& Yildirim, Dogan…[et al.]. 2018. The Diagnostic Value of Irisin in Pediatric Patients with Acute Abdominal Pain. Emergency Medicine International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1157053
Modern Language Association (MLA)
Sarac, Fatma…[et al.]. The Diagnostic Value of Irisin in Pediatric Patients with Acute Abdominal Pain. Emergency Medicine International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1157053
American Medical Association (AMA)
Sarac, Fatma& Buyukbese Sarsu, Sevgi& Yeniocak, Selman& Sahin, Kamil& Yucetas, Esma& Yildirim, Dogan…[et al.]. The Diagnostic Value of Irisin in Pediatric Patients with Acute Abdominal Pain. Emergency Medicine International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1157053
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1157053