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Efficacy and Safety of Duhuo Jisheng Decoction for Postmenopausal Osteoporosis: A Systematic Review and Meta-Analysis
Joint Authors
Li, Zhe
Li, Jinyu
Du, Jian
Feng, Guiyu
Kang, Shengqian
Zhu, Weifeng
Shang, Hongcai
Wang, Wei
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-15
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Aim.
To evaluate the effects and medication safety of Duhuo Jisheng Decoction (DHJSD) alone or as a combination therapy with other interventions on the related clinical index in postmenopausal osteoporosis condition.
Methods.
Search in CNKI, WanFang, CBM, VIP, PubMed, EMBASE, and Cochrane Library databases and randomized controlled trials where at least one group received any form of DHJSD for postmenopausal osteoporosis condition.
Risk of bias was based on the Cochrane handbook, the quality of evidence was assessed by the GRADEpro online, and analyses were performed by RevMan 5.3 software.
Results.
Eight studies were enrolled with 650 participants.
DHJSD alone or with other interventions had a significant effect on BMD of the lumbar spine (MD = 0.46, 95%CI (0.24, 0.68), P<0.0001), E2 (SMD = 0.49, 95%CI (0.30, 0.68), P<0.0001), and clinical effectiveness (OR = 5.07, 95%CI (3.07, 8.35), P<0.0001).
However, no effect at BGP (MD = −0.84, 95%CI (−1.69, 0.00), P=0.05) was seen.
Conclusion.
The pooled estimate suggested that DHJSD combined with conventional medical therapies has a certain clinical curative effect on postmenopausal osteoporosis.
However, considering the unsatisfactory quality of included trials, more high-quality trials are needed to elucidate this issue.
American Psychological Association (APA)
Li, Jinyu& Wang, Wei& Feng, Guiyu& Du, Jian& Kang, Shengqian& Li, Zhe…[et al.]. 2020. Efficacy and Safety of Duhuo Jisheng Decoction for Postmenopausal Osteoporosis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1157129
Modern Language Association (MLA)
Li, Jinyu…[et al.]. Efficacy and Safety of Duhuo Jisheng Decoction for Postmenopausal Osteoporosis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1157129
American Medical Association (AMA)
Li, Jinyu& Wang, Wei& Feng, Guiyu& Du, Jian& Kang, Shengqian& Li, Zhe…[et al.]. Efficacy and Safety of Duhuo Jisheng Decoction for Postmenopausal Osteoporosis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1157129
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1157129