![](/images/graphics-bg.png)
Clinicopathological Significance of Heat Shock Protein (HSP) 27 Expression in Gastric Cancer: A Updated Meta-Analysis
Joint Authors
Liu, Tong
Liu, Duo
Kong, Xiangxue
Dong, Mei
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Aim.
HSP27 is a protein chaperone protecting cell from heat shock, and upregulated HSP27 expression has been found in many different cancers.
We conduct this update meta-analysis to evaluate the relationship between HSP27 expression and clinicopathological features.
Methods.
We searched PubMed, Chinese CNKI, and WanFang databases to identify studies that assessed the association between clinicopathological feature and HSP27 expression in gastric cancer patients.
Results.
We found overexpression of HSP27 was associated with incidence of gastric cancer (OR = 6.31, 95% CI = 1.10–36.15, P<0.0001).
However, there was no significant difference between HSP27 expression and gastric cancer differentiation, gender difference, lymph node metastasis, and distant metastasis.
Conclusion.
Our meta-analysis study indicates that overexpression of HSP27 is associated with incidence of gastric cancer statistically.
American Psychological Association (APA)
Liu, Tong& Liu, Duo& Kong, Xiangxue& Dong, Mei. 2020. Clinicopathological Significance of Heat Shock Protein (HSP) 27 Expression in Gastric Cancer: A Updated Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1157150
Modern Language Association (MLA)
Liu, Tong…[et al.]. Clinicopathological Significance of Heat Shock Protein (HSP) 27 Expression in Gastric Cancer: A Updated Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1157150
American Medical Association (AMA)
Liu, Tong& Liu, Duo& Kong, Xiangxue& Dong, Mei. Clinicopathological Significance of Heat Shock Protein (HSP) 27 Expression in Gastric Cancer: A Updated Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1157150
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1157150