GC Method Validation for the Analysis of Menthol in Suppository Pharmaceutical Dosage Form
Joint Authors
Jaradat, Nidal
Abualhasan, Murad N.
Mousa, Ayman
Zaid, A. N.
Source
International Journal of Analytical Chemistry
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-06
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Menthol is widely used as a fragrance and flavor in the food and cosmetic industries.
It is also used in the medical and pharmaceutical fields for its various biological effects.
Gas chromatography (GC) is considered to be a sensitive method for the analysis of menthol.
GC chromatographic separation was developed using capillary column (VF-624) and a flame ionization detector (FID).
The method was validated as per ICH guidelines for various parameters such as precision, linearity, accuracy, solution stability, robustness, limit of detection, and quantification.
The tested validation parameters were found to be within acceptable limits.
The method was successfully applied for the quantification of menthol in suppositories formulations.
Quality control departments and official pharmacopeias can use our developed method in the analysis of menthol in pharmaceutical dosage formulation and raw material.
American Psychological Association (APA)
Abualhasan, Murad N.& Zaid, A. N.& Jaradat, Nidal& Mousa, Ayman. 2017. GC Method Validation for the Analysis of Menthol in Suppository Pharmaceutical Dosage Form. International Journal of Analytical Chemistry،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1157500
Modern Language Association (MLA)
Jaradat, Nidal…[et al.]. GC Method Validation for the Analysis of Menthol in Suppository Pharmaceutical Dosage Form. International Journal of Analytical Chemistry No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1157500
American Medical Association (AMA)
Abualhasan, Murad N.& Zaid, A. N.& Jaradat, Nidal& Mousa, Ayman. GC Method Validation for the Analysis of Menthol in Suppository Pharmaceutical Dosage Form. International Journal of Analytical Chemistry. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1157500
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1157500