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Yiqi Yangyin Huoxue Method in Treating IdiopathicPulmonary Fibrosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Joint Authors
Zhou, Min
Ye, Chao
Liang, Qijun
Pei, Qiulan
Xu, Fan
Wen, Hang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-03
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Objective.
Idiopathic pulmonary fibrosis (IPF) is a common respiratory disease that can lead to respiratory failure in severe condition.
Despite notable advances in its treatment, some patients show poor effect when treated with conventional western medicine (CWM).
Traditional Chinese medicine with the Yiqi Yangyin Huoxue method (YQYYHXM) has been reported to be positive for IPF.
In order to explore the effectiveness and safety of YQYYHXM in the treatment of IPF, we performed this meta-analysis.
Method.
We searched six databases including Embase, Cochrane, PubMed, CNKI, Wan Fang, and VIP database from their inception to June 1, 2019, and then selected eight studies.
Two reviewers independently conducted methodological evaluation and data analysis by the software RevMan 5.3.3 and Stata 12.0.
Results.
The meta-analysis revealed that when YQYYHXM was adopted in combination with CWM, cough, chest pain, and shortness of breath of IPF patients improved significantly.
After treatment with YQYYHXM combined with CWM, the SGRQ of IPF patients substantially enhanced.
YQYYHXM also has positive effect on 6MWD and TLC, but the improvement on FVC was not obvious.
In addition, YQYYHXM has no significance in improving PaO2.
All the adverse events were reported in the control group.
Conclusion.
YQYYHXM is more effective and safe as adjunctive treatment for patients with IPF.
However, in the future, long-term, large-scale, and high-quality trials will be required to provide more convincing evidence of YQYYHXM due to some limitations of this review.
American Psychological Association (APA)
Zhou, Min& Ye, Chao& Liang, Qijun& Pei, Qiulan& Xu, Fan& Wen, Hang. 2020. Yiqi Yangyin Huoxue Method in Treating IdiopathicPulmonary Fibrosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1157562
Modern Language Association (MLA)
Zhou, Min…[et al.]. Yiqi Yangyin Huoxue Method in Treating IdiopathicPulmonary Fibrosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-15.
https://search.emarefa.net/detail/BIM-1157562
American Medical Association (AMA)
Zhou, Min& Ye, Chao& Liang, Qijun& Pei, Qiulan& Xu, Fan& Wen, Hang. Yiqi Yangyin Huoxue Method in Treating IdiopathicPulmonary Fibrosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1157562
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1157562