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Alkaloids from Plants with Antimalarial Activity: A Review of Recent Studies
Author
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-12
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Malaria is one of the major health problems in developing countries.
The disease kills a large number of people every year and also affects financial status of many countries.
Resistance of the plasmodium parasite, the causative agent, to the existing drugs, including chloroquine, mefloquine, and artemisinin based combination therapy (ACT), is a serious global issue in malaria treatment and control.
This warrants an urgent quest for novel compounds, particularly from natural sources such as medicinal plants.
Alkaloids have over the years been recognized as important phytoconstituents with interesting biological properties.
In fact, the first successful antimalarial drug was quinine, an alkaloid, which was extracted from Cinchona tree.
In the present review work, the alkaloids isolated and reported recently (2013 till 2019) to possess antimalarial activity are presented.
Several classes of alkaloids, including terpenoidal, indole, bisindole, quinolone, and isoquinoline alkaloids, were identified with a promising antimalarial activity.
It is hoped that the reports of the review work will spur further research into the structural modification and/or development of the interesting compounds as novel antimalarial drugs.
American Psychological Association (APA)
Uzor, Philip F.. 2020. Alkaloids from Plants with Antimalarial Activity: A Review of Recent Studies. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-17.
https://search.emarefa.net/detail/BIM-1157914
Modern Language Association (MLA)
Uzor, Philip F.. Alkaloids from Plants with Antimalarial Activity: A Review of Recent Studies. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-17.
https://search.emarefa.net/detail/BIM-1157914
American Medical Association (AMA)
Uzor, Philip F.. Alkaloids from Plants with Antimalarial Activity: A Review of Recent Studies. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-17.
https://search.emarefa.net/detail/BIM-1157914
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1157914