Human Theta Burst Stimulation Combined with Subsequent Electroacupuncture Increases Corticospinal Excitability
Joint Authors
Li, Jiali
Ren, Meng
Wang, Wenjing
Xu, Shutian
Zhang, Sicong
Li, Yuanli
Shan, Chunlei
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
Intermittent theta burst stimulation (iTBS) is a widely used noninvasive brain stimulation for the facilitation of corticospinal excitability (CSE).
Previous studies have shown that acupuncture applied to acupoints associated with motor function in healthy people can reduce the amplitude of the motor-evoked potentials (MEPs), which reflects the inhibition of CSE.
In our work, we wanted to test whether the combination of iTBS and electroacupuncture (EA) would have different effects on CSE in humans.
Methods.
A single-blind sham-controlled crossover design study was conducted on 20 healthy subjects.
Subjects received 20 minutes’ sham or real EA stimulation immediately after sham or real iTBS.
MEPs, short-interval intracortical inhibition (SICI), intracortical facilitation (ICF), cortical silent period (CSP), and central motor conduction time (CMCT) were recorded before each trial, and immediately, 20 minutes, and 40 minutes after the end of stimulation.
Results.
In the sham iTBS group, EA produced a reduction in MEPs amplitude, lasting approximately 40 minutes, while in the real iTBS group, EA significantly increased MEPs amplitude beyond 40 minutes after the end of stimulation.
In sham EA group, the recorded MEPs amplitude showed no significant trend over time compared to baseline.
Among all experiments, there were no significant changes in SICI, ICF, CSP, CMCT, etc.
Conclusion.
These data indicate that immediate application of EA after iTBS significantly increased corticospinal excitability.
This trial was registered in the Chinese Clinical Trial Registry (registration no.
ChiCTR1900025348).
American Psychological Association (APA)
Li, Jiali& Ren, Meng& Wang, Wenjing& Xu, Shutian& Zhang, Sicong& Li, Yuanli…[et al.]. 2020. Human Theta Burst Stimulation Combined with Subsequent Electroacupuncture Increases Corticospinal Excitability. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1158011
Modern Language Association (MLA)
Li, Jiali…[et al.]. Human Theta Burst Stimulation Combined with Subsequent Electroacupuncture Increases Corticospinal Excitability. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1158011
American Medical Association (AMA)
Li, Jiali& Ren, Meng& Wang, Wenjing& Xu, Shutian& Zhang, Sicong& Li, Yuanli…[et al.]. Human Theta Burst Stimulation Combined with Subsequent Electroacupuncture Increases Corticospinal Excitability. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1158011
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158011