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In Vitro and In Vivo Wound Healing and Anti-Inflammatory Activities of Babassu Oil (Attalea speciosa Mart. Ex Spreng., Arecaceae)
Joint Authors
Santos, José Alex A.
Silva, José Wellinton da
Santos, Simone Maria dos
Rodrigues, Maria de Fátima
Silva, Camila Joyce A.
da Silva, Márcia Vanusa
Correia, Maria Tereza S.
Albuquerque, Julianna F. C.
Melo, Cristiane M. L.
Silva, Teresinha G.
Martins, René D.
Aguiar Júnior, Francisco Carlos A.
Ximenes, Rafael M.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-24
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Babassu (Attalea speciosa Mart.
ex Spreng., Arecaceae) is a palm tree endemic to Brazil and found mainly in the borders of Amazon forest, where the harvesting of its fruits is an important source of income for more than 300,000 people.
Among the communities of coconut breakers women, babassu oil is used in culinary, as fuel, and mostly as medicinal oil for the treatment of skin wounds and inflammation.
This study aimed to evaluate in vitro and in vivo the wound healing effects of babassu oil.
In vitro, babassu oil increased the migration of L929 fibroblasts, inhibited the production of nitric oxide by LPS-stimulated peritoneal macrophages, and increased the levels of INF-γ and IL-6 cytokines production.
In vivo, babassu oil accelerated the healing process in a full-thickness splinted wound model, by an increase in the fibroblasts number, blood vessels, and collagen deposition in the wounds.
The babassu oil also increased the recruitment of inflammatory cells into the wound site and showed an anti-inflammatory effect in a chronic ear edema model, reducing ear thickness, epidermal hyperplasia, and myeloperoxidase activity.
Thus, these data corroborate the use of babassu oil in folk medicine as a remedy to treat skin wounds.
American Psychological Association (APA)
Santos, José Alex A.& Silva, José Wellinton da& Santos, Simone Maria dos& Rodrigues, Maria de Fátima& Silva, Camila Joyce A.& da Silva, Márcia Vanusa…[et al.]. 2020. In Vitro and In Vivo Wound Healing and Anti-Inflammatory Activities of Babassu Oil (Attalea speciosa Mart. Ex Spreng., Arecaceae). Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1158126
Modern Language Association (MLA)
Santos, José Alex A.…[et al.]. In Vitro and In Vivo Wound Healing and Anti-Inflammatory Activities of Babassu Oil (Attalea speciosa Mart. Ex Spreng., Arecaceae). Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1158126
American Medical Association (AMA)
Santos, José Alex A.& Silva, José Wellinton da& Santos, Simone Maria dos& Rodrigues, Maria de Fátima& Silva, Camila Joyce A.& da Silva, Márcia Vanusa…[et al.]. In Vitro and In Vivo Wound Healing and Anti-Inflammatory Activities of Babassu Oil (Attalea speciosa Mart. Ex Spreng., Arecaceae). Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1158126
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158126