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Variations of Flavone Glycosides Profile Underscore the Necessity of Quality Control of Prepared Microctis Folium Slices
Joint Authors
Yuan, Min
Li, Kun-Ping
Liu, Chang-Le
Liang, Ze-yu
Pan, Tian-Ling
Guo, Jiao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-27
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Microctis Folium (MF), the dried leaves of Microcos paniculata, is widely used as a medical and food dual-purpose herb in South-east Asia and China.
However, the quality control of MF is not well studied.
A simple and reliable quality control method was urgently needed for its growing usage.
Herein, at first, its main active components were identified by UPLC-ESI-qTOF-MS, and a representative MF flavone glycosides profile consisting of ten compounds was illustrated, which is the most detailed one up to now.
Successively, using vitexin as the reference substance, a novel QAMS method with HPLC for quantification of the ten identified flavone glycosides was developed and methodologically validated.
Furthermore, making use of the abovementioned QAMS method, quantitative profiling of 21 batches of prepared MF slices collected from different hospital pharmacies were performed.
As a result, the total contents of ten flavone glucosides and the content of specific compound showed obvious variations.
Using the ten compounds’ contents dataset, the 21 batches of samples were divided into two distinct clusters by HCA.
In sum, our results indicated that it was of great importance to take quality control of prepared MF slices and we presented a robust and simple method for their quantitative determination, which should be beneficial for the quality control of MF and its derived products.
American Psychological Association (APA)
Li, Kun-Ping& Yuan, Min& Liu, Chang-Le& Liang, Ze-yu& Pan, Tian-Ling& Guo, Jiao. 2020. Variations of Flavone Glycosides Profile Underscore the Necessity of Quality Control of Prepared Microctis Folium Slices. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1158203
Modern Language Association (MLA)
Li, Kun-Ping…[et al.]. Variations of Flavone Glycosides Profile Underscore the Necessity of Quality Control of Prepared Microctis Folium Slices. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1158203
American Medical Association (AMA)
Li, Kun-Ping& Yuan, Min& Liu, Chang-Le& Liang, Ze-yu& Pan, Tian-Ling& Guo, Jiao. Variations of Flavone Glycosides Profile Underscore the Necessity of Quality Control of Prepared Microctis Folium Slices. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1158203
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158203