Solid-State Fermentation of Aspergillus niger to Optimize Extraction Process of Isoliquiritigenin from Glycyrrhiza uralensis
Joint Authors
Liu, Jiahui
Jing, Yunrong
Ji, Yubin
Hao, Jingwei
Li, Dianwei
Zhang, Lei
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We successfully extracted isoliquiritigenin from Glycyrrhiza uralensis via fermentation with Aspergillus niger and ultrasonic-assisted extraction.
In brief, we used A.
niger fermentation to culture G.
uralensis powder, and we optimized some key parameters such as reaction conditions of pH, inoculation concentration of A.
niger, fermentation time, and solid-liquid ratio.
Based on a single-factor experiment, we utilized the response surface methodology (RSM) approach to optimize this extraction procedure.
Using the RSM approach, optimized conditions of pH = 3.694, the solid-liquid ratio = 1 : 2.155, and the inoculation concentration of A.
niger = 1466745 were selected.
Optimized conditions resulted in an extraction efficiency of 1.525 mg/g.
These results showed that the extraction of isoliquiritigenin was most affected by pH and then the time of fermentation and the solid-liquid ratio.
Overall, the developed extraction technique yielded 5 times the amount of isoliquiritigenin when compared to traditional methods.
American Psychological Association (APA)
Hao, Jingwei& Li, Dianwei& Jing, Yunrong& Zhang, Lei& Liu, Jiahui& Ji, Yubin. 2020. Solid-State Fermentation of Aspergillus niger to Optimize Extraction Process of Isoliquiritigenin from Glycyrrhiza uralensis. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1158262
Modern Language Association (MLA)
Hao, Jingwei…[et al.]. Solid-State Fermentation of Aspergillus niger to Optimize Extraction Process of Isoliquiritigenin from Glycyrrhiza uralensis. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1158262
American Medical Association (AMA)
Hao, Jingwei& Li, Dianwei& Jing, Yunrong& Zhang, Lei& Liu, Jiahui& Ji, Yubin. Solid-State Fermentation of Aspergillus niger to Optimize Extraction Process of Isoliquiritigenin from Glycyrrhiza uralensis. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1158262
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158262