Extreme Oncoplastic Surgery for MultifocalMulticentric and Locally Advanced Breast Cancer
Joint Authors
Koppiker, Chaitanyanand B.
Noor, Aijaz Ul
Dixit, Santosh
Busheri, Laleh
Sharan, Gautam
Dhar, Upendra
Allampati, Hari Kiran
Nare, Smeeta
Source
International Journal of Breast Cancer
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
Breast conserving surgery (BCS) followed by radiation therapy (RT) has become the preferred alternative to mastectomy for patients with early stage breast cancer (BC).
Randomized trials have confirmed equivalent locoregional control and overall survival for BCS and mastectomy.
Extreme Oncoplasty (EO) extends the indications of BCS for patients who would otherwise require mastectomy, ensuring better aesthetic outcomes and oncological safety.
Methods.
BC patients with multifocal/multicentric (MF/MC) tumors, extensive DCIS, or large tumor >50mm underwent EO at our breast unit.
Therapeutic reduction mammaplasty (TRM) with wise pattern preoperative markings and dual pedicle technique involving parenchymal rearrangement was used for oncoplastic reconstructions in majority of the cases followed by RT.
Patient reported outcome measures (PROMs) were assessed using the validated Breast-Q questionnaire.
Results.
Of the 39 patients in the study, 36 had unilateral and 3 had bilateral BC.
Mean age was 47.2 years.
Median tumor size was 75mm.
17 (43.6%) patients received NACT; none achieved a complete clinical response.
28 (71.8%) patients were administered to adjuvant chemotherapy.
33(84.6%) patients received RT to the breast with a median dose of 50Gy in 28 fractions and a boost dose of 10Gy in 5 fractions to the tumor bed.
No major complications or local recurrences were observed.
Excellent Breast-Q scores were observed in patients undergoing EO after 12 months of follow-up.
Conclusion.
EO followed by RT results in acceptable local-regional control, low rate of complications, and high patient satisfaction.
In selected patients, EO could provide a safe alternative for breast conservation surgery instead of mastectomy.
American Psychological Association (APA)
Koppiker, Chaitanyanand B.& Noor, Aijaz Ul& Dixit, Santosh& Busheri, Laleh& Sharan, Gautam& Dhar, Upendra…[et al.]. 2019. Extreme Oncoplastic Surgery for MultifocalMulticentric and Locally Advanced Breast Cancer. International Journal of Breast Cancer،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1158284
Modern Language Association (MLA)
Koppiker, Chaitanyanand B.…[et al.]. Extreme Oncoplastic Surgery for MultifocalMulticentric and Locally Advanced Breast Cancer. International Journal of Breast Cancer No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1158284
American Medical Association (AMA)
Koppiker, Chaitanyanand B.& Noor, Aijaz Ul& Dixit, Santosh& Busheri, Laleh& Sharan, Gautam& Dhar, Upendra…[et al.]. Extreme Oncoplastic Surgery for MultifocalMulticentric and Locally Advanced Breast Cancer. International Journal of Breast Cancer. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1158284
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158284