Verification of the Functional Antioxidant Activity and Antimelanogenic Properties of Extracts of Poria cocos Mycelium Fermented with Freeze-Dried Plum Powder
Joint Authors
Kim, Jong-Jin
Kang, Kyung-Yun
Yee, Sung-Tae
Hwang, Yun-Ho
Lee, Sung-Ju
Jang, Ho-Yeol
Hong, Seong-Gyeol
Mun, Seul-Ki
Kim, Su-Jin
Park, Kuyng-Wuk
Seo, Kyoung-Sun
Ban, Seung-Eon
Jin, Seong-Woo
Kim, Hyuck-Joo
Source
International Journal of Biomaterials
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-02
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Here we examine the effects of extracts of Poria cocos mycelium fermented with freeze-dried plum powder (PPE) on the α-melanocyte stimulating hormone (α-MSH)-stimulated melanogenesis in cultured murine B16 melanoma cells (B16 cells), relative to the effects of Prunus extract.
We found that an extract of Prunus fermentation showed significant inhibition of melanogenesis and tyrosinase activity with no effect on cell proliferation and was more active compared to Prunus extract alone.
Furthermore, we confirmed that medium containing 3% Prunus was the optimal culture substrate for fermentation with Poria cocos.
These results provide evidence that Prunus fermentation extract affects skin whiting in murine B16 melanoma cells (B16 cells).
Prunus contains rutin, oxalic acid, succinic acid, and fumaric acid, which help in digestion and fatigue recovery.
The rutin of Prunus mume is reported to have antioxidant and anti-inflammatory effects.
Also, Prunus extract has a tyrosinase inhibitory activity for skin whiting through its antioxidant activity.
Therefore, we believe the Prunus extract for Poria cocos fermentation can be provided as a potential mediator to induce skin whiting.
American Psychological Association (APA)
Kang, Kyung-Yun& Hwang, Yun-Ho& Lee, Sung-Ju& Jang, Ho-Yeol& Hong, Seong-Gyeol& Mun, Seul-Ki…[et al.]. 2019. Verification of the Functional Antioxidant Activity and Antimelanogenic Properties of Extracts of Poria cocos Mycelium Fermented with Freeze-Dried Plum Powder. International Journal of Biomaterials،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1158441
Modern Language Association (MLA)
Kang, Kyung-Yun…[et al.]. Verification of the Functional Antioxidant Activity and Antimelanogenic Properties of Extracts of Poria cocos Mycelium Fermented with Freeze-Dried Plum Powder. International Journal of Biomaterials No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1158441
American Medical Association (AMA)
Kang, Kyung-Yun& Hwang, Yun-Ho& Lee, Sung-Ju& Jang, Ho-Yeol& Hong, Seong-Gyeol& Mun, Seul-Ki…[et al.]. Verification of the Functional Antioxidant Activity and Antimelanogenic Properties of Extracts of Poria cocos Mycelium Fermented with Freeze-Dried Plum Powder. International Journal of Biomaterials. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1158441
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158441